Treponema pallidum subspecies pallidum – the Causative Agent of Neurosyphilis
Authors:
Salavec Miloslav 1; Boštíková Vanda 2; Vaňásková Zuzana 3; Smetana Jan 2; Sleha Radek 2; Coufalová Monika 2; Plíšek Stanislav 4; Špliňo Miroslav 2; Štěpánová Vlasta 5; Boštík Pavel
Authors‘ workplace:
Klinika nemocí kožních a pohlavních, FN a LF UK, Hradec Králové
1; Katedra epidemiologie, FVZ UO, Hradec Králové
2; Odborná neurologická ordinace, Hradec Králové
3; Klinika infekčních nemocí, FN a LF UK, Hradec Králové
4; Ústav klinické mikrobiologie, FN a LF UK Hradec Králové
5; Centrum pokročilých studií, FVZ UO, Hradec Králové
6
Published in:
Epidemiol. Mikrobiol. Imunol. 62, 2013, č. 3, s. 91-99
Overview
Neurosyphilis is defined as infection of central nervous system by Treponema pallidum subspecies pallidum. Neurosyphilis can develop at any stage after initial infection and is reflected in laboratory results. The pathogenesis of neurosyphilis is similar to that of classical form of syphilis. Individuals with persistent abnormalities in the cerebrospinal fluid are at risk of the development of clinical manifestations. Proper understanding of particular forms of neurosyphilis for differential diagnosis is important to determine potential risk of the development of progressive disease in neurology.
Keywords:
neurosyphilis – Treponema pallidum – meningitis – meningovascular disease – differential diagnosis
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Labels
Hygiene and epidemiology Medical virology Clinical microbiologyArticle was published in
Epidemiology, Microbiology, Immunology
2013 Issue 3
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