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Bazovská S., Ďurovská J., Pancák J., Záborská M., Derdáková. M.: Lyme Borreliosis and Demyelinating Disease of the Central Nervous System


Authors: S. Bazovská 1;  J. Ďurovská 2;  J. Pancák 2;  M. Záborská 3;  M. Derdáková. 4
Authors‘ workplace: Ústav epidemiológie, Lekárska fakulta UK v Bratislave 1;  I. neurologická klinika, Univerzitná nemocnica v Bratislave 2;  Mikrobiologický ústav, Lekárska fakulta UK v Bratislave 3;  Parazitologický ústav SAV v Košiciach 4
Published in: Epidemiol. Mikrobiol. Imunol. 60, 2011, č. 1, s. 45-47

Overview

A case report is presented of a 55-year-old patient diagnosed with a demyelinating disease of unclear etiology. The patient had Lyme borreliosis in 2004. Specific IgG antibodies against B. burgdorferi s. l. were detected in the serum. Intrathecal antibodies were not found in the cerebrospinal fluid, but the presence of B. garinii DNA was confirmed by PCR analysis. It can be hypothesized that the borrelial persistence in the body may have been one of the triggers of the autoimmune process resulting in demyelination of the central nervous system (CNS).

Keywords:
demyelinating disease of the CNS – B. garinii DNA in the cerebrospinal fluid.


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Labels
Hygiene and epidemiology Medical virology Clinical microbiology

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Epidemiology, Microbiology, Immunology

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2011 Issue 1

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