Changes in thyroid cytology reporting in the 3rd edition of the Bethesda system
Authors:
Dušková J.
Authors‘ workplace:
CGOP – Laboratoř patologie, Next Clinics, a. s., Praha
; Topelex, s. r. o., Praha
; Ústav patologie 1. LF UK a VFN, Praha
Published in:
Čes.-slov. Patol., 60, 2024, No. 1, p. 64-67
Category:
Reviews Article
Overview
Reporting fine-needle aspiration of thyroid nodules in the Bethesda classification is a practice widely used internationally and by us. The revised third edition of the Bethesda System of Reporting Thyroid Cytopathology brings changes in terminology, content, and new chapters. In terms of terminology, an obvious change is the removal of the two-word names of three categories while maintaining the six diagnostic categories of the previous versions - new: BI – non-diag- nostic, BIII – atypia of undetermined significance, BIV – follicular neoplasia. In the detailed description of the findings within the individual categories, the ter- minological changes adopted by the fifth edition of the WHO classification of thyroid neoplasia are respected - in particular, the recommended name follicular thyroid nodular disease for the most frequently represented category BII - benign. In the evaluation itself, the diagnostic specifications accepted by the current WHO classification of histopathological findings are reflected in the individual categories - if they are applicable at the cytological level. Targeted attention will need to be paid to high grade features. The revised version brings new chapters dedicated to molecular testing and evaluation of the paediatric population.
Keywords:
thyroid nodules, neoplasms of thyroid gland, FNAB of thyroid gland, thyroid cancer, The Bethesda system for reporting thyroid cyto-logy 2023
Sources
- Jiskra J. Diagnostika a další péče o pacienty s tyreoidalnimi uzly: Doporučení American Thyroid Association 2015 modifikované pro podmínky České republiky. [Management of patients with thyroid nodules: American Thyroid Association guidelines in the settingof Czech republic]. Cas Lek Cesk 2017; 156(5): 241-251.
- Delellis RA, Lloyd RV, Heitz PU, Eng C, (Eds.):. World Health Organization classifi- cation of tumours. Pathology & genetics of tumours of endocrine organs ed.). Lyon: IAR Press; 2004:
- Ali SZ, Cibas ES. The Bethesda system for re- porting thyroid cytopathology : Definitions, criteria, and explanatory notes ed.). New York: Springer; 2010:
- Duskova J. Nový systém pro sjednocené hodnocení tenkojehlových aspiračních bi- opsií štítné žlázy – Bethesda 2010. [The new system for reporting fine needle aspiration bi- opsies of the thyroid gland: Bethesda 2010]. Cesk Patol 2011; 47(1): 8-14.
- Dušková J. Nový systém mezinárodně sjed- noceného hodnocení tenkojehlových aspi- račních biopsií štítné žlázy: Bethesda klasifik- ace 2010. DMEV 2010; 13(4): 191-195.
- Ali SZ. The Bethesda system for reporting thyroid cytopathology : Definitions, criteria, and explanatory notes ed.). New York, NY: Springer Science+Business Media; 2018:
- Dušková J. Aktualizované Bethesda hodno- cení aspiračních biopsií štítné žlázy tenkou jehlou. DMEV 2018; 21(4): 202-209.
- Duskova J. Aktuální otázky tenkojehlové aspirační biopsie štítné žlázy. Current issues in fine needle aspiration biopsy of thyroid gland. Cesk Patol 2019; 55(1): 13-23.
- WHO Classification of Tumours Editorial Board. Endocrine and neuroendocrine tu- mours [Internet]. Lyon (France): International Agency for Research on Cancer; 2022 [cited 2023 08 20]. (WHO classification of tumours series, 5th ed.; vol. 10). Available from: https:// tumourclassification.iarc.who.int/chapters/53
- Baloch ZW, Asa SL, Barletta JA, et al. Over- view of the 2022 WHO classification of thyroid neoplasms. Endocr Pathol 2022; 33(1): 27-63.
- Basolo F, Macerola E, Poma AM, Torregros- sa L. The 5(th) edition of who classification of tumors of endocrine organs: Changes in the diagnosis of follicular-derived thyroid carci- noma. Endocrine 2023;
- Jung CK, Bychkov A, Kakudo K. Update from the 2022 World Health Organization classification of thyroid tumors: A standard- ized diagnostic approach. Endocrinol Metab (Seoul) 2022; 37(5): 703-718.
- Nosé V, Ericson LA, Lopes MBS, Tischler AS. Diagnostic pathology endocrine (3rd ed.). Philadelphia: Elsevier; 2023: 4-75.
- Ali SZ, Vanderlaan PaE. The Bethesda sys- tem for reporting thyroid cytopathology. Definitions, criteria, and explanatory notes.(3rd ed.). Springer; 2023: 300.
- Ali SZ, Baloch ZW, Cochand-Priollet B, et al. The 2023 Bethesda system for reporting thy- roid cytopathology. Thyroid 2023;
- Han M, 2023.00005. FFBSFRTCaURJCTPDJ. Bethesda system for reporting thyroid cyto- pathology–an updated review. J Clin Transl Pathol 2023; 3(2): 84-98.
- Lloyd RV, Osamura RY, Klöppel G, Rosai J. WHO classification of tumours of endocrine organs (4th ed.). Lyon: IARC; 2017: 355.
- Nikiforova MN, Lepe M , Tolino LA, et al. Thyroid cytology smear slides: An untapped resource for thyroseq testing. Cancer Cyto- pathol 2021; 129(1): 33-42.
- Dušková, J. Jaké změny přináší 5. vydání WHO klasifikace nádorů tyreoidálních tu- morů do klinicko-patologické spolupráce? DMEV 2023; 26(4): 139-144.
- Dušková, J. Změny v hodnocení a hlášení tenkojehlových biopsií štítné žlázy související s 3. vydáním Bethesda systému. DMEV 2023; 26(4): 145-150.
Labels
Anatomical pathology Forensic medical examiner ToxicologyArticle was published in
Czecho-Slovak Pathology
2024 Issue 1
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