„Burned-out“ tumour of a testis with metastasis to retroperitoneal lymph node
Authors:
Karol Kajo 1; Michal Kajo 1; Katarína Macháleková 1; Július Palaj 2; Iveta Mečiarová 3; Peter Zuzák 4; Emil Tvrdík 5
Authors‘ workplace:
Ústav patológie SZU a OÚSA, s. r. o., Bratislava
1; Klinika onkologickej chirurgie OÚSA, s. r. o., a LF UK, Bratislava
2; Alpha medical patológia, s. r. o., Bratislava
3; Interná onkologická klinika OÚSA a TU, Bratislava
4; sv. VINCENT, s. r. o., Prievidza
5
Published in:
Ces Urol 2014; 18(2): 138-143
Category:
Case report
Overview
The term “burned-out tumour” refers to a rare clinical entity that represents a complete spontaneous regression of previously untreated testicular cancer with metastases in the retroperitoneum, mediastinum, lymph nodes, lung or liver. We describe the case of a 55-year-old patient with pain in the right lumbar region, in which the CT scan disclosed a tumour mass in the retroperitoneum (sized 70 × 55 × 90 mm), and ultrasonography revealed structural changes in the lower pole of the right testicle. First, the patient underwent a right-sided orchiectomy with histological finding of a scar in the testicle without distinct tumour changes, followed by radical resection of the retroperitoneal tumour, which histology proved to be a metastasis of seminoma in the lymph node. Consequently, the histology in the testis was re-evaluated and determined to be a completely regressed testicular tumour – “burned-out tumour.” Subsequently, patient underwent adjuvant chemotherapy. The pathogenesis of “burned-out” tumours are comprises mainly of immunological factors, ischemia represents another, although less probable cause. Prognosis of “burned-out” tumours in cases of seminomatous germ cell tumours is comparable with those of primary testicular tumours.
Key words:
“burned-out”, regression, seminoma, testis, tumour.
Sources
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Labels
Paediatric urologist Nephrology UrologyArticle was published in
Czech Urology
2014 Issue 2
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