The use of molecular genetics in the differential diagnosis of renal tumors
Authors:
Jindřich Branžovský 1; Petr Martínek 1; Kevin Baulet 1; Ivan Trávníček 2; Petr Stránský 2; Tomáš Vaneček 1; Milan Hora 2; Ondřej Hes 1
Authors‘ workplace:
Šiklův patologicko-anatomický ústav LF UK a FN, Plzeň
1; Urologická klinika LF UK a FN, Plzeň
2
Published in:
Ces Urol 2012; 16(4): 214-221
Category:
Review article
Overview
Renal tumors are a highly heterogenous group of tumors which makes their diagnosis increasingly complicated. The use of molecular and genetic techniques has resulted not only in the improvement of classification and differential diagnosis, but has also led to a better understanding of the biological behavior of these tumors. The increasing use of targeted therapy makes precise diagnosis of each lesion important and in the future it may become a crucial tool for the selection of proper treatment.
Key words:
kidney, renal cell carcinoma, oncocytoma, translocation renal cell carcinoma, morphology, molecular biology, diagnostics, genetics, biological treatment, differential diagnostics.
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Paediatric urologist Nephrology UrologyArticle was published in
Czech Urology
2012 Issue 4
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