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Possible Conservative Procedure in the Treatment of Infants with Low Risk Neuroblastome


Authors: J. Štěrba;  J. Skotáková;  P. Gál;  P. Múdrý
Authors‘ workplace: Oddělení dětské onkologie, FN Brno - Dětská nemocnice, primář MUDr. J. Štěrba, PhD. Klinika dětské radiologie, FN Brno - Dětská nemocnice, přednosta doc. MUDr. J. Procházka, CSc. Klinika dětské chirurgie, traumatologie a ortopedie, FN Brno - Dětská nemocn
Published in: Čes-slov Pediat 2002; (2): 72-74.
Category:

Overview

Neuroblastoma is the most common malignant tumour in infants. For all Patients with neuroblastoma, age, stage, and tumour biology (such as MYCN copy number, DNA Ploidy, type of histology) are the most important variables influencing Prognosis. Children less than ope year-old with localized tumours have a five-year survival in more than 90 %, whereas in older children with advanced disease the long-term survival is less than 30 %, despite very intensive therapy.In younger patients with localized disease it is aPPropriate to test Possible ways of declining treatment intensity, reducing thus treatment - related morbidity and mortality. There is increasing evidence in the literature that spontaneous regression is Possible in some neuroblastomas, but standard treatment in infants with localized disease is sbil immediate surgical resection. In this Paper two Patients with localized neuroblastoma are Presented where the „wait and watch aPProach" was successfully used, incl. a review of the literature.

Key words:
low risk neuroblastoma, surgery risk, follow-uP

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Labels
Neonatology Paediatrics General practitioner for children and adolescents
Topics Journals
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