Clonal Melanocytic Naevi
Authors:
L. Pock 1; M. Kotrlá 2; L. Drlík 3
Authors‘ workplace:
Bioptická laboratoř s. r. o., Plzeň odborná vedoucí lékařka prof. MUDr. Alena Skálová, CSc.
1; Dermatologická ordinace s. r. o., Červená Voda
2; Dermatovenerologické oddělení, Šumperská nemocnice, a. s. prim. MUDr. Lubomír Drlík
3
Published in:
Čes-slov Derm, 90, 2015, No. 1, p. 13-19
Category:
Pharmacologyand Therapy, Clinical Trials
Overview
Clonal naevi are compound and intradermal naevocellular naevi with a focus of differently pigmented melanocytes occurring in their intradermal component. Clinically this clone looks as a darker region in a former naevus showing on dermoscopy a structureless area of blue, blue-gray, blue-black or dark brown colour. Histologically the darker area exhibits a localized group of greater epithelioid melanocytes admixed with melanophages in the intradermal component of the naevus. It is important to differentiate the clonal naevus from melanoma. Total excision with histological diagnosis is a sufficient therapy. The authors report series of cases with clonal melanocytic nevi.
Key words:
clonal naevi – combined naevi – clinical picture – dermoscopic picture – histopathologic correlation – therapy
Sources
1. BALL, N. J., GOLITZ, L. E. Melanocytic nevi with focal atypic epithelioid cell components: A review of seventy-three cases. J. Am. Acad. Dermatol., 1994, 30, p. 724–729.
2. HIGH, W. A., ALANEN, K. W., GOLITZ, L. E. Is melanocytic nevus with focal atypical epithelioid component (clonal nevus) a superficial variant of deep penetrating nevus? J. Am. Acad. Dermatol., 2006, 55, 3, p. 460–466.
3. LUZUR, B., BASTIAN, B. C., CALONJE, E. Melanocytic nevi. In Calonje, E., Brenn, T., Lazar, A., McKee, P. H., eds. McKee’s Pathology of the skin with clinical correlations. (4th ed). China: Elsevier Saunders, 2012, p. 1151–1220, ISBN 978-1-4160-5649-2.
3. MASSI, G., LEBOIT, P. E. Histological Diagnosis of Nevi and Melanoma. 2nd ed. Berlin: Springer, 2014, 752 p., ISBN978-3-642-37310-7.
4. POCK, L. Atypické melanocytární léze. Čes.-slov. Derm., 2013, 88, 3, p. 107–122.
Labels
Dermatology & STDs Paediatric dermatology & STDsArticle was published in
Czech-Slovak Dermatology
2015 Issue 1
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