Transepidermal Water Loss Measurement (TEWL)

Czech version

Authors: V. Resl ¹; M. Leba ¹; I. Rampl ²
Authors‘ workplace: Dermatovenerologická klinika LF UK a FN Plzeň přednosta prof. MUDr. Karel Pizinger, CSc. ¹; Fakulta elektroniky a komunikačních technologií Vysokého učení technického v Brně a Enjoy spol. s r. o. vedoucí doc. ing. Ivan Rampl, CSc. ²
Published in: Čes-slov Derm, 83, 2008, No. 6, p. 319-324
Category: New drugs, cosmetics, devices

Overview

Transepidermal water loss measurement (TEWL) is a method frequently used for study of skin barrier function under physiologic and pathologic condition to objectification and specification of clinical diagnosis, to evaluation of irritation tests, to follow-up of effects of drugs and cosmetics. Today, three types of measuring devices are used: closed, ventilated and open chambers. Currently commercially available devices are introduced. Their pro-and-cons, necessity of method standardization, the most frequent sources of mistakes and method wide use are discussed. The example of TEWL measurement applied together with other bioengineering methods in ongoing research project is attached.

Key words:
transepidermal water loss – TEWL – non-invasive skin function testing – standardization of measurement – bioengineering of the skin – physiologic functions measurement – dermato-cosmetic measurement – measurement of TEWL in pathologic conditions

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Article was published in

Czech-Slovak Dermatology

2008 Issue 6