Can be considered the primary fallopian tube cancer an enigma at the beginning of the third millenium?

Czech version

Authors: J. Špaček ¹; J. Laco ²; J. Petera ³; I. Sedláková ¹; A. Řezáč ¹
Authors‘ workplace: Porodnická a gynekologická klinika LF UK a FN, Hradec Králové, přednosta doc. MUDr. J. Špaček, Ph. D., IFEPAG ¹; Fingerlandův ústav patologie LF UK a FN, Hradec Králové, přednosta prof. MUDr. A. Ryška, Ph. D. ²; Klinika onkologie a radioterapie LF UK a FN, Hradec Králové, přednosta prof. MUDr. J. Petera, Ph. D. ³
Published in: Ceska Gynekol 2013; 78(6): 501-508
Category: Original Article

Overview

Objective:
To analyze differences between primary fallopian tube cancer and ovarian cancer.

Design:
Overview study.

Setting:
Department of Obstetrics and Gynecology, The Fingerland Department of Pathology, Department of Oncology and Radiotherapy, Faculty of Medicine and University Hospital Hradec Kralove.

Methods:
Overview study focused on analysis of data of primary fallopian tube cancer.

Conclusion:
The incidence of primary fallopian tube cancer was thought to be very low in the past but it is very difficult to assess the primary origin in the case of advanced disease (ovary versus fallopian tube). Tumorogenic potential of endosalpinx in relation to epithelial tumours is much more bigger. According to the current knowledge, the vast majority of high-grade serous carcinomas of the “ovary“ in fact arise in the mucosa of fimbrial portion of fallopian tube.

Keywords:
primary fallopian tube cancer – ovarian cancer – BRCA mutation – risk factors – paraaortic lymphadenectomy

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