Radikalita chirurgické léčby a postaveníadjuvantní chemoterapie u nádorů ovariahraniční malignity

Overview

Objective:
Evaluation of the benefi t of the radical surgical therapy in the assessment of prognosticfactors and indication of adjuvant therapy in patients with borderline tumors of ovary.Design: Retrospective study.Setting: Department of Obstetrics and Gynecology, University Hospital, Ostrava.Methods: The group consists of 26 patients operated on our department, 12 of which underwentrestaging operation after insuffi cient primary surgery in different hospital and14 underwentprimary surgery in our department. The average age was 42.9 years.Results: Radical surgery with regional lymphadenectomy was performed in 18 cases (69%) andnon-radical in 8 cases (31%). In 7 patients (27%) fertility preservation operation was done. Accordingto histological results 19 tumors (73%) were of serous type, 7 being of mucinous type(27%). There were no other histological types in our group. The lymphnodes were positive in 4cases (22%) out of 18. Eight patients were indicated for adjuvant chemotherapy (31%), 4 of themfor regional lymphnodes positivity, 2 for peritoneal implants, 1 patient for tumor residuum. Thelast case was a patient with tumor duplicity of a borderline tumor of ovary stage FIGO IIC andcorporal carcinoma stage FIGO IB.We had one case of recurrence after fertility preservation surgery. There was no case of pregnancyyet.Conclusions: Borderline tumors of ovary have good prognosis and low recurrence rate. In spiteof that, there exists a group of women with higher risk of recurrence and disease progressionwhich can be fatal. These patients may benefi t from adjuvant therapy, which is indicated afterevaluation of risk factors ideally acquired from the radical surgery.

Klíčová slova:
borderline tumor of ovary, radical surgery, lymphadenectomy, chemotherapy