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Phenylpropanoids and flavonoid from Helichrysum petiolare Hilliard & B. L. Burtt


Authors: Renata Kubínová;  Marcela Nejezchlebová;  Markéta Gazdová;  Mária Gáborová;  Ivana Várady;  Lenka Molčanová
Published in: Čes. slov. Farm., 2021; 70, 206-209
Category: Original Article
doi: https://doi.org/https://doi.org/10.5817/CSF2021-6-206

Overview

The phytochemical analysis of a  methanolic extract from Helichrysum petiolare Hilliard & B. L. (Asteraceae) confirmed the content of phenylpropanoids and flavonoids. Five secondary metabolites were isolated using preparative HPLC, namely coumarin scopolin (1), 3-chlorogenic acid (2), caffeic acid-hexose derivative (3), dicaffeoylquinic acid (5), and the flavonoid isoquercitrin (4). These compounds were identified from this species for the first time. Only dicaffeoylquinic acid was able to inhibit Escherichia coli CCM 7929 at the concertation of 512 μg ∙ mL–1 in a screening of antibacterial activity.

Keywords:

HPLC – antibacterial activity – Helichrysum petiolare – plant phenols


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