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Neurodegenerative Dementias


Authors: I. Rektorová
Authors‘ workplace: Centrum pro kognitivní poruchy a demence, I. neurologická klinika LF MU a FN u sv. Anny v Brně
Published in: Cesk Slov Neurol N 2009; 72/105(2): 97-109
Category: Minimonography

Overview

An article is focused on evaluati on and diagnostics of a patient with cognitive deficit and dementia. Mild cognitive impairment is characterized and a brief review of the most common types of neurodegenerative dementias is provided: Alzheimer’s disease, dementia with Lewy bodies/ Parkinson’s disease dementia, frontotemporal lobar degeneration and Huntington’s disease.

Key words:
dementia – mild cognitive impairment – Alzheimer’s disease – Parkinson’s disease with dementia – dementia with Lewy bodies – frontotemporal dementia – Huntington’s disease


Sources

1. Growdon JH, Rossor MN (eds). The dement as II. Philadelphia: Elsevi er 2007.

2. Rektorová I. Demence. In: Rektor I et al (eds). Centrální poruchy motoriky a demence. Plzeň: Adéla 2003: 10– 33.

3. Hort J, Rusina R et al (eds). Paměť a její poruchy. Paměť z hlediska neurovědního a klinického. Praha: Maxdorf 2007.

4. Ritchie K, Lovestone S. The dementias. Lancet 2002; 360(9347): 1759– 1766.

5. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM- IV). Washington: American Psychiatric Association 1994:143– 147.

6. Konrád J. Deprese, pseudodemence, demence. In: Rektorová I (ed). Kognitivní poruchy a demence. Praha: Triton 2007: 21– 28.

7. Rektorová I. Diferenciální diagnostika demencí. Psychiatrie 2004; 3: 216– 224.

8. Folstein MF, Folstein SE, McHughs PR. „Mini Mental State“. A practical method for grading the cognitive state of patients for the clinician. J Psychiatric Res 1975; 12(3): 189– 198.

9. Mathuranath PS, Nestor PJ, Berri os GE, Rakowicz W, Hodges JR. A brief cognitive test battery to differentiate Alzheimer’s disease and frontotemporal dementia. Neurology 2000; 55(11): 1613– 1620.

10. Cummings JL, Mega M, Gray K, Rosenberg-Thompson, Carusi DA, Gornbein J. The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 1994; 44(12): 2308– 2314.

11. Waldemar G, Dubois B, Emre M, Georges J, Mc-Keith IG, Rossor M et al. Recommendations for the diagnosis and management of Alzheimer‘s disease and other disorders associated with dementia: EFNS guideline. Eur J Neurol 2007; 14(1): e1– e26.

12. Ressner P, Hort J, Rektorová I, Bartoš A, Rusina R, Línek V et al. Doporučené postupy pro diagnostiku Alzheimerovy nemoci a dalších onemocnění spojených s demencí. Cesk Slov Neurol N 2008; 71/ 104(5): 494– 501.

13. Koukolík F, Jirák R. Neurobiologie, klinický obraz, terapie. Praha: Galén 2004.

14. Hort J. Markery demence. In: Rektorová I (ed). Kognitivní poruchy a demence. Praha: Triton 2007: 10– 20.

15. Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV et al. Current concepts in mild cognitive impairment. Arch Neurol 2001; 58(12): 1985– 1992.

16. Petersen RC, Stevens JC, Ganguli M, Tangalos EG, Cummings JL, DeKosky ST. Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2001; 56(9): 1133– 1142.

17. Cummings JL. Alzheimer‘s disease. N Engl J Med 2004; 351(1): 56– 67.

18. Matěj R, Koukolík F. Neuropatologie neurodegenerativních demencí. In: Rektorová I (ed). Kognitivní poruchy a demence. Praha: Triton 2007: 89– 108.

19. Imbimbo BP, Lombard J, Pomara N. Pathophysiology of Alzheimer‘s disease. Neuroimaging Clin N Am 2005; 15(4): 727– 753.

20. Scarpini E, Scheltens P, Feldman H. Treatment of Alzheimer’s disease: current status and new perspectives. Lancet Neurol 2003; 2(9): 539– 547.

21. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer‘s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer‘s Disease. Neurology 1984; 34(7): 939– 944.

22. Dubois B, Feldman HH, Jacova C, Dekosky ST, Barberger-Gateau P, Cummings J et al. Research criteria for the diagnosis of Alzheimer‘s disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 2007; 6(8): 734– 746.

23. Consensus report of the Working Group on: Molecular and biochemical markers of Alzheimer’s disease. The Ronald and Nancy Reagan Research Institute of the Alzheimer’s Association and the National Institute on Aging Working Group. Neurobiol Aging 1998; 19(2): 109– 116.

24. Hort J, Glosová L, Vyhnálek M, Bojar M, Škoda D, Hladíková M. Tau protein a beta amyloid v likvoru u Alzheimerovy choroby. Cesk Slov Neurol N 2007; 70/ 103(1): 30– 36.

25. Bartoš A. Klinické novinky na poli Alzheimerovy nemoci. In: Rektorová I (ed) Kognitivní poruchy a demence. Praha: Triton 2007: 49– 60.

26. Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP et al. Imaging brain amyloid in Alzheimer‘s disease with Pittsburgh Compo und-B. Ann Neurol 2004; 55(3): 306– 319.

27. Rosenberg RN. Immunotherapy for Alzheimer disease: the promise and the problem. Arch Neurol 2005; 62(10): 1506– 1507.

28. Sheardová K, Hort J, Rusina R, Bartoš A, Línek V, Ressner P et al. Doporučené postupy pro léčbu Alzheimerovy nemoci a dalších onemocnění spojených s demencí. Cesk Slov Neurol N 2007; 70/ 103: 589– 597.

29. Rektorová I, Rektor I. Parkinsonský syndrom. In: Rektor I, Rektorová I et al (eds). Centrální poruchy hybnosti v praxi. Movement disorders. Praha: Triton 2003: 21– 70.

30. Rektorová I. Demence u Parkinsonovy nemoci a jiných extrapyramidových onemocnění. In: Růžička E et al (eds). Diferenciální diagnostika a léčba demencí. Příručka pro praxi. Praha: Galén 2003: 99– 112.

31. Rektorová I. Demence u Parkinsonovy nemoci. Čes Ger Rev 2008; 6: 214– 219.

32. Burn DJ, McKeith IG. Current treatment of dementia with Lewy bodies and dementia associated with Parkinson’s disease. Mov Disord 2003; 18 (Suppl 6): S72– S79.

33. Aarsland D, Andersen K, Larsen JP, Lolk A, Kragh- Sørensen P. Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study. Arch Neurol 2003; 60(3): 387– 392.

34. Cools R, Swainson R, Owen AM et al. Cognitive dysfunction in non-demented Parkinson’s disease. In: Wolters ECh, Scheltens PH and Berendse HW (eds). Mental Dysfunction in Parkinson’s disease II. Amsterdam: Academic Pharmaceutical Productions 1999: 142– 164.

35. Dubois B, Pillon B. Cognitive deficits in Parkinson’s disease. J Neurol 1997; 244(1): 2– 8.

36. Lees AJ, Smith E. Cognitive deficits in the early stages of Parkinson’s disease. Brain 1983; 106(2): 257– 270.

37. Galvin JE, Pollack J, Morris JC. Clinical phenotype of Parkinson disease dementia. Neurology 2006; 67(9): 1605– 1611.

38. Janvin CC, Larsen JP, Salmon DP, Galasko D, Hugdahl K, Aarsland D. Cognitive profiles of individual patients with Parkinson‘s disease and dementia: comparison with dementi a with Lewy bodies and Alzheimer‘s disease. Mov Disord 2006; 21(3): 337– 342.

39. Jellinger KA. What is new in degenerative dementi a disorders? Wien Klin Wochenschr 1999; 111(17): 682– 704.

40. McKeith IG, Dickson DW, Emre M, O‘Bri en JT, Feldman H, Cummings J et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology 2005; 65(12): 1863– 1872.

41. Dubois B, Burn D, Goetz C, Aarsland D, Brown RG, Broe GA et al. Diagnostic procedures for Parkinson‘s disease dementia: recommendations from the movement disorder society task force. Mov Disord 2007; 22(16): 2314– 2324.

42. Rektorova I, Srovnalova H, Kubikova R, Prasek J. Striatal dopamine transporter imaging correlates with depressivew symptoms and Tower of London task performance in Parkinson’s disease. Mov Disord 2008; 23(11): 1580– 1587.

43. Emre M, Cummings JL, Lane RM. Rivastigmine in dementia associated with Parkinson‘s disease and Alzheimer‘s disease: similarities and differences. J Alzheimers Dis 2007; 11(4): 509– 519.

44. Rektorová I, Baláž M. Postup u psychotických komplikací Parkinsonovy nemoci. In: Rektor I et al (eds). Parkinsonova nemoc: doporučené postupy diagnostiky a léčby II. Pozdní stadium. Praha: Galén 2004: 23– 25.

45. Rektorová I. Farmakoterapi e Parkinsonovy nemoci. Farmakoterapie 2007; 6: 611– 617.

46. Burton EJ, McKeith IG, Burn DJ, Willi ams ED, O’Bri en JT. Cerebral atrophy in Parkinson‘s disease with and without dementia: a comparison with Alzheimer‘s disease, dementia with Lewy bodies and controls. Brain 2004; 127(4): 791– 800.

47. Nagano–Saito A, Washimi Y, Arahata Y, Kachi T, Lerch JP, Evans AC et al. Cerebral atrophy and its relation to cognitive impairment in Parkinson disease. Neurology 2005; 64: 224– 229.

48. Braak H, Del Tredici K, Rüb U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson‘s disease. Neurobiol Aging 2003; 24(2): 197– 211.

49. Braak H, Rüb U, Jansen Steur EN, Del Tredici K, de Vos RA. Cognitive status correlates with neuropathologic stage in Parkinson disease. Neurology 2005; 64(8): 1404– 1410.

50. Aarsland D, Perry R, Brown A, Larsen JP, Ballard C. Neuropathology of dementia in Parkinson‘s disease: a prospective, community-based study. Ann Neurol 2005; 58(5): 773– 776.

51. Rektorová I. Kognitivní a behaviorální poruchy u demence při Parkinsonově nemoci a u demence s Lewyho tělísky. Neurol pro praxi 2004; 1: 15– 21.

52. Williams DR, de Silva R, Paviour DC, Pittman A, Watt HC, Kilford L et al. Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson‘s syndrome and PSP- parkinsonism. Brain 2005; 128(6): 1247– 1258.

53. Burn DJ, O’Brien JT. Use of functional imaging in Parkinsonism and dementia. Mov Disord 2003; 18 (Suppl 6): S88– S95.

54. Rektorova I. DaTSCAN for diagnosis. EPNN Journal 2007; 11(1): 14– 15.

55. Poewe W. Treatment of dementia with Lewy bodies and Parkinson’s disease dementia. Mov Disord 2005; 20 (Suppl 12): S77– S82.

56. Rektorová I. Psychiatrické symptomy Parkinsonovy nemoci: diagnostika a léčba. Neurol pro praxi 2007; 8: 291– 294.

57. Rektorová I. Účinek donepezilu na demenci u Parkinsonovy nemoci a Alzheimerovy nemoci: Pilotní studie. Cesk Slov Neurol N 2004; 67/ 100(5): 359– 363.

58. McKeith IG, Del Ser T, Spano P, Emre M, Wesnes K, Anand R et al. Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo- controlled international study. Lancet 2000; 356(9247): 2031– 2036.

59. Emre M, Aarsland D, Albanese A, Byrne EJ, Deuschl G, De Deyn PP et al. Rivastigmine for dementia associated with Parkinson’s disease. N Engl J Med 2004; 351(24): 2509– 2518.

60. Rektorová I. Rivastigmin v léčbě demence u Parkinsonovy nemoci. Remedia 2006; 6: 609– 613.

61. Rektorová I. Frontotemporální lobární degenerace – diagnóza z neuro-psychiatrického pomezí. Neurol pro praxi 2006; 4:199– 202.

62. Rektorová I. Frontotemporální lobární degenerace. In: Rektorová I (ed) Kognitivní poruchy a demence. Praha: Triton 2007: 61– 75.

63. Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 1998; 51(6): 1546– 1554.

64. McKhann GM, Albert MS, Grossman M, Miller B, Dickson D, Trojanowski JQ; Work Group on Frontotemporal Dementia and Pick‘s Disease. Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick‘s Disease. Arch Neurol 2001; 58(11): 1803– 1809.

65. Hodges JR, Davies RR, Xuereb JH, Casey B, Broe M, Bak TH et al. Clinicopathological correlates in frontotemporal dementia. Ann Neurol 2004; 56(3): 399– 406.

66. Kertesz A, McMonagle P, Blair M, Davidson W, Munoz DG. The evolution and pathology of frontotemporal dementia. Brain 2005; 128(9): 1996– 2005.

67. Godbolt AK, Josephs KA, Revesz T, Warrington EK, Lantos P, King A et al. Sporadic and familial dementia with ubiquitin-positive tau-negative inclusions: clinical features of one histopathological abnormality underlying frontotemporal lobar degeneration. Arch Neurol 2005; 62(7): 1097– 1101.

68. Mackenzie IR, Baker M, Pickering-Brown S, Hsiung GY, Lindholm C, Dwosh E et al. The neuropathology of frontotemporal lobar degeneration caused by mutations in the progranulin gene. Brain 2006; 129(11): 3081– 3090.

69. Mott RT, Dickson DW, Trojanowski JQ, Zhukareva V, Lee VM, Forman M et al. Neuropathologic, biochemical, and molecular characterization of the frontotemporal dementias. J Neuropathol Exp Neurol 2005; 64(5): 420– 428.

70. Bigio EH. Update on recent molecular and genetic advances in frontotemporal lobar degeneration. J Neuropathol Exp Neurol 2008; 67(7): 635– 648.

71. Bigio EH. TAR DNA-binding protein-43 in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer disease. Acta Neuropathol 2008; 116(2): 135– 140.

72. Huey ED, Putnam KT, Grafman J. A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia. Neurology 2006; 66(1): 17– 22.

73. Victor M, Ropper AH. Huntington chorea. In: Adams RD, Victor M. Principles of Neurology. 7th ed. Columbus, Ohio: The McGraw-Hill Companies 2001: 1121– 1125.

74. Vonsattel JP, DiFigli a M. Huntington’s disease. J Neuropathol Exp Neurol 1998; 57(5): 369– 384.

75. Roth J, Židovská J, Uhrová T, Doubek P, Havrdová E, Koblihová J et al. Huntingtonova nemoc a etické problémy její diagnostiky. Psychiatrie 2001; 4: 251– 255.

76. Rektorová I. Chorea. In: Rektor I, Rektorová I et al (eds). Centrální poruchy hybnosti v praxi. Movement disorders. Praha: Triton 2003: 103– 107.

77. Claes S, Van Zand K, Legius E, Dom R, Malfroid M et al. Correlations between triplet repeat expansion and clinical features in Huntington’s disease. Arch Neurol 1996; 53(8): 714– 715.

78. Berardelli A, Noth J, Thompson PD, Bollen EL, Curra A, Deuschl G et al. Pathophysiology of chorea and bradykinesia in Huntington’s disease. Mov Dis 1999; 14(3): 398– 403.

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