Peripartální kardiomyopatie –
diagnostika a léčba

Czech version

Authors: Poloczková H.
Authors‘ workplace: I. interní kardioangiologická klinika LF MU a FN u sv. Anny v Brně
Published in: Kardiol Rev Int Med 2018, 20(4): 260-263

Overview

Peripartum cardiomyopathy is a relatively rare disease characterised by systolic heart failure (HF) on the base of left ventricular systolic dysfunction occurring at the end of pregnancy or in the months following the delivery in previously healthy women. The course of the disease may vary, restitution of the left ventricular function is seen in more than 50% of cases, while some patients have a serious course of the disease with progression of HF to cardiogenic shock requiring heart transplantation or mechanical circulatory support. About 20% of patients develop chronic HF with persistent dysfunction of the left ventricle. Early diagnosis and treatment are very important for these patients but may be complicated by the fact that the symptoms are similar to those present in healthy women without heart failure at the end of pregnancy (such as short breath, palpitation, swollen legs or fatigue). The aetiology of the disease is still unclear, the vascular/hormonal hypothesis being most discussed at present. The incidence of the disease varies geographically. The disease appears in 80–90% postpartum, only a small number of cases are diagnosed during pregnancy.

Key words:

peripartum cardiomyopathy – heart failure – aetiology – diagnosis – treatment

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