Fixed‑dose triple antihypertensive combination and subclinical organ damage

Czech version

Authors: P. Wohlfahrt
Authors‘ workplace: Centrum kardiovaskulární prevence, 1. LF UK a Thomayerova nemocnice, PrahaKardiocentrum, Pracoviště preventivní kardiologie, IKEM, PrahaMezinárodní centrum klinického výzkumu, FN u sv. Anny, Brno
Published in: Kardiol Rev Int Med 2015, 17(3): 249-252
Category: Cardiology Review

Overview

Most patients with arterial hypertension require a combination of two or more antihypertensive drugs in order to achieve target levels of blood pressure. On the other hand, with an increasing number of tablets, adherence and persistence with antihypertensive therapy may worsen. Fixed‑dose combination of antihypertensive drugs simplifies therapy for the patient and allows target blood pressure levels to be achieved with a lower number and doses of antihypertensive drugs. In the present case report we describe the positive effect of a new fixed‑dose triple antihypertensive therapy on parameters of subclinical organ damage in a patient with a history of poor adherence to antihypertensive therapy.

Keywords:
arterial hypertension – fixed‑dose combination – subclinical organ damage – left ventricular hypertrophy – chronic kidney disease

Sources

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