PLOS Genetics - Číslo 9/2012

Perspective

32767

Heterozygous Mutations in DNA Repair Genes and Hereditary Breast Cancer: A Question of Power

GWAS of Diabetic Nephropathy: Is the GENIE out of the Bottle?

The Conflict within and the Escalating War between the Sex Chromosomes

The Long Path from QTL to Gene

Research Article

32767

Proteome-Wide Analysis of Disease-Associated SNPs That Show Allele-Specific Transcription Factor Binding

Exome Sequencing Identifies Rare Deleterious Mutations in DNA Repair Genes and as Potential Breast Cancer Susceptibility Alleles

A Gene Family Derived from Transposable Elements during Early Angiosperm Evolution Has Reproductive Fitness Benefits in

Genome-Wide Association Study for Serum Complement C3 and C4 Levels in Healthy Chinese Subjects

Role of Transposon-Derived Small RNAs in the Interplay between Genomes and Parasitic DNA in Rice

Co-Evolution of Mitochondrial tRNA Import and Codon Usage Determines Translational Efficiency in the Green Alga

SIRT6/7 Homolog SIR-2.4 Promotes DAF-16 Relocalization and Function during Stress

CNV Formation in Mouse Embryonic Stem Cells Occurs in the Absence of Xrcc4-Dependent Nonhomologous End Joining

Tetraspanin Is Required for Generation of Reactive Oxygen Species by the Dual Oxidase System in

Citrullination of Histone H3 Interferes with HP1-Mediated Transcriptional Repression

Variation in Genes Related to Cochlear Biology Is Strongly Associated with Adult-Onset Deafness in Border Collies

The Long Non-Coding RNA Affects Chromatin Conformation and Expression of , but Does Not Regulate Its Imprinting in the Developing Heart

Rif2 Promotes a Telomere Fold-Back Structure through Rpd3L Recruitment in Budding Yeast

Is a Metastasis Susceptibility Gene That Suppresses Metastasis by Modifying Tumor Interaction with the Cell-Mediated Immunity

The p38/MK2-Driven Exchange between Tristetraprolin and HuR Regulates AU–Rich Element–Dependent Translation

Rare Copy Number Variants Contribute to Congenital Left-Sided Heart Disease

A Genetic Basis for a Postmeiotic X Versus Y Chromosome Intragenomic Conflict in the Mouse

An Essential Role of Variant Histone H3.3 for Ectomesenchyme Potential of the Cranial Neural Crest

Characterization of Inducible Models of Tay-Sachs and Related Disease

Hominoid-Specific Protein-Coding Genes Originating from Long Non-Coding RNAs

Transcriptional Repression of Hox Genes by HP1/HPL and H1/HIS-24

Integrative Genomic Analysis Identifies Isoleucine and CodY as Regulators of Virulence

Convergence of the Transcriptional Responses to Heat Shock and Singlet Oxygen Stresses

Genomics of Adaptation during Experimental Evolution of the Opportunistic Pathogen

Enrichment of HP1a on Drosophila Chromosome 4 Genes Creates an Alternate Chromatin Structure Critical for Regulation in this Heterochromatic Domain

Vsx2 Controls Eye Organogenesis and Retinal Progenitor Identity Via Homeodomain and Non-Homeodomain Residues Required for High Affinity DNA Binding

TCF7L2 Modulates Glucose Homeostasis by Regulating CREB- and FoxO1-Dependent Transcriptional Pathway in the Liver

The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems

Complex Chromosomal Rearrangements Mediated by Break-Induced Replication Involve Structure-Selective Endonucleases

Factors That Promote H3 Chromatin Integrity during Transcription Prevent Promiscuous Deposition of CENP-A in Fission Yeast

A Mimicking-of-DNA-Methylation-Patterns Pipeline for Overcoming the Restriction Barrier of Bacteria

Determinants of Human Adipose Tissue Gene Expression: Impact of Diet, Sex, Metabolic Status, and Genetic Regulation

Genome-Wide Association Studies Identify Heavy Metal ATPase3 as the Primary Determinant of Natural Variation in Leaf Cadmium in

Tethering of the Conserved piggyBac Transposase Fusion Protein CSB-PGBD3 to Chromosomal AP-1 Proteins Regulates Expression of Nearby Genes in Humans

A Genome-Wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans

Normal DNA Methylation Dynamics in DICER1-Deficient Mouse Embryonic Stem Cells

H4K20me1 Contributes to Downregulation of X-Linked Genes for Dosage Compensation

The NDR Kinase Scaffold HYM1/MO25 Is Essential for MAK2 MAP Kinase Signaling in

Coevolution within and between Regulatory Loci Can Preserve Promoter Function Despite Evolutionary Rate Acceleration

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

SWI/SNF-Like Chromatin Remodeling Factor Fun30 Supports Point Centromere Function in

A Response Regulator Interfaces between the Frz Chemosensory System and the MglA/MglB GTPase/GAP Module to Regulate Polarity in

Functional Variants in and Involved in Activation of the NF-κB Pathway Are Associated with Rheumatoid Arthritis in Japanese

Two Distinct Repressive Mechanisms for Histone 3 Lysine 4 Methylation through Promoting 3′-End Antisense Transcription

Genetic Modifiers of Chromatin Acetylation Antagonize the Reprogramming of Epi-Polymorphisms

UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development

A Comparison of Brain Gene Expression Levels in Domesticated and Wild Animals

PLOS Genetics

2012 Číslo 9

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