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Léky proti rakovinné buňce jako zdravotní péče lékařský koncept pro farmaceutický lék

Lorlatinib showed significant benefit in 1st line treatment of advanced ALK-positive non-small cell lung carcinoma

30. 3. 2021 Source: Genetic Profile and Treatment of NSCLC

In the international CROWN study, lorlatinib compared to crizotinib led to a 72% reduction in the risk of disease progression or death and significant improvement in intracranial response to treatment in previously untreated patients with advanced ALK-positive non-small cell lung carcinoma (NSCLC). The results were published in November 2020 in the prestigious New England Journal of Medicine.

Position of Parenteral Therapy in Patients with Severe COVID-19 Disease

Patients with severe COVID-19 disease are at risk of developing acute respiratory insufficiency requiring non-invasive or invasive pulmonary ventilation. Intensive care therapy is associated with a…

30. 3. 2021 Source: Parenteral Nutrition

Prevalence of Depression, Anxiety, and Stress in the Global Population During the COVID-19 Pandemic

A cross-sectional study assessed the prevalence and rate of depression, anxiety, and stress among individuals from various countries around the world during the ongoing COVID-19 pandemic and initial…

30. 3. 2021 Source: Depression and Anxiety

Does idarucizumab reverse the anticoagulant effect of dabigatran regardless of renal function?

The drugs idarucizumab and dabigatran are excreted by the kidneys. The RE-VERSE AD study investigated whether the renal function of patients affects the extent of the reversing effect of idarucizumab…

29. 3. 2021 Source: Anticoagulant Treatment

Profile of the effect of aclidinium bromide compared to glycopyrronium bromide

A study by Spanish authors examined the profiles of 2 long-acting muscarinic receptor antagonists (LAMA), aclidinium bromide and glycopyrronium bromide, under in vitro and in vivo conditions.

29. 3. 2021 Source: Treatment of Asthma and COPD

Genuair®/Pressair® Inhaler in the Treatment of COPD –⁠ Minimum Errors During Inhalation and High Patient Satisfaction

The article by German authors summarizes the results achieved with the Genuair® inhaler (marketed in the USA under the name Pressair®), highlighting its ease of use, simple patient training, low…

29. 3. 2021 Source: Treatment of Asthma and COPD

The Importance of Vitamin D for the Proper Function of the Immune System

The relationship between vitamin D and the immune system has been known for nearly 30 years, but only in recent years have we gained new insights that explain and further refine the physiological…

29. 3. 2021 Source: GI, colic and microbiome

Summary of Recommendations for the Treatment of Immune Thrombocytopenia in Pregnancy

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a temporary or permanent reduction in the number of platelets, leading to an increased risk of bleeding. It also occurs in 1-5…

28. 3. 2021 Source: Immune Thrombocytopenia

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Teriflunomide and Pregnancy Planning

The authors of the article published last year in Multiple Sclerosis Journal present data regarding experiences with the use of teriflunomide during pregnancy.

25. 3. 2021 Source: Multiple Sclerosis

Interactive Case Study of a Patient with Severe Hemophilia A -⁠ Experience from Slovenia

Assoc. Prof. Dr. Irena Preložnik Zupan (University Medical Centre Ljubljana) describes an interactive case study of a patient with severe hemophilia A and progressive cataracts in both eyes.

24. 3. 2021 Source: Quality Life Even with Hemophilia

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