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Otrava etanolem a psychotropními látkami u případu s hnilobnými změnami


: Hiroshi Kinoshita 1;  Naoko Tanaka 1;  Mostofa Jamal 1;  Mitsuru Kumihashi 1;  Ayaka Takakura 1;  T. Tobiume 1;  Kunihito Tsutsui 2;  Kiyoshi Ameno 1
: Department of Forensic Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan 1;  Health Sciences, School of Nursing, Faculty of Medicine, Kagawa University, Kagawa, Japan 2
: Soud Lék., 60, 2015, No. 2, p. 25-27
: Original Article

Je prezentován případ smrtelné otravy paroxetinem, flunitrazepamem a etanolem v terénu hnilobných změn. Kvantitativní toxikologická analýza vykázala, že koncentrace paroxetinu a 7-aminoflunitrazepamu ( metabolitu flunitrazepamu) ve vzorku femorální krve byla 0,28 µg/ml a 0.17 µg/ml. Také byla zjištěna hladina alkoholu 2,90 mg/ml a n-propanolu 0,10 mg/ml. Usuzujeme proto, že smrt nastala v důsledku vzájemné interakce paroxetinu, flunitrazepamu a etanolu. Bylo též uvažováno o vlivu hnilobných změn na forensní toxikologické vyhodnocení.

Klíčová slova:
flunitrazepam – etanol – paroxetine – plynová chromatografie s hmotnostní spektrometrií (GC/MS).


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Anatomical pathology Forensic medical examiner Toxicology
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