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Analysis of meningococcal vaccine uptake in patients with invasive meningococcal disease, Czech Republic, 2006–2022


Authors: P. Křížová 1;  Z. Okonji 1,2;  M. Honskus 1,2
Authors‘ workplace: Národní referenční laboratoř pro meningokokové nákazy, Centrum epidemiologie a mikrobiologie, Státní zdravotní ústav, Praha 1;  3. lékařská fakulta Univerzity Karlovy, Praha 2
Published in: Epidemiol. Mikrobiol. Imunol. 72, 2023, č. 4, s. 243-247
Category: Short Communication

Overview

In 2006–2022, 958 cases of invasive meningococcal disease (IMD) were reported to the surveillance programme in the Czech Republic, of which 21 (2.19%) had a history of vaccination with one of the meningococcal vaccines. Data analysis shows that these vaccines provide a very good protection against IMD. It was found that vaccinated patients with IMD either were not vaccinated against the causative serogroup and/or did not receive a booster dose. The results of this analysis show the benefit of both vaccines available in the Czech Republic: recombinant vaccine containing meningococcal serogroup B antigens (MenB vaccine) and tetravalent conjugate vaccine containing antigens of four meningococcal serogroups A, C, W, Y (A, C, W, Y conjugate vaccine). The results also show the benefit of meningococcal vaccine booster doses and the need for giving MenB vaccine to young children as early as possible.


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Hygiene and epidemiology Medical virology Clinical microbiology
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