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Circulation of Coxsackieviruses in the Slovak Population in 1985-2007


Authors: M. Sojka;  S. Bopegamage;  A. Petrovičová
Authors‘ workplace: Oddelenie virológie, Slovenská zdravotnícka univerzita, Bratislava
Published in: Epidemiol. Mikrobiol. Imunol. 57, 2008, č. 2, s. 57-60

Overview

Enteroviral infections are of the most common infections in the human population. Circulation of these viruses is high in population and they cause a wide range of clinical syndromes in human. The aim of this study was to compare the coxsackievirus circulation intensity in the population of the Slovak Republic during the period of last 23 years and to identify changes also in relation to modification in polio vaccination scheme. Marker indicating suffered infection was the presence of virus specific antibodies, assessed by means of the virus-neutralizing test. High frequency of infections by all studied coxsackievirus serotypes was confirmed in this study. Consecutive decrease in rate of anti-coxsackievirus antibodies was identified. This may be a consequence of hygiene standard improvement. After modification of immunization scheme (2004/2005) the decrease has been stopped, a mild increase of seropositivity to all studied serotypes was observed, respectively.

Keywords:
enteroviruses, circulation, coxsackievirus, virus neutralization test


Sources

1. Galama, J. Enteroviral infections in the immunocompromized host. Rev of Med Microbiol, 1997, 3, 33 – 40.

2. Hyoty, H., Hiltunen, M., Knip, M., Laakkonen, M., Vahasalo, P., Karjalainen, J., Koskela, P., Roivainen, M., Leinikki, P., Hovi, T., Akerblom, H. K. A perspective study of the role of Coxsackie B and other enterovirus infections in the pathogenesis of IDDM. The Childhood Diabetes in Finland (DiMe) Study group. Diabetes, 1995, 44, 652 – 657.

3. Hyoty, H., Taylor, K. W. The role of viruses in human diabetes. Diabetologia, 2002, 45, 1353 – 1361.

4. King, A. M. Q., Brown, F., Christian, P., Hovi, T., Hyypiä, T., Knowles, N. J., Lemon, S. M., Minor, P. D., Palmenberg, A. C., Skern, T., Stanway, G. Picornaviridae. In Virus Taxonomy, Seventh Report of the International Committee for Taxonomy of Viruses. Eds Van Regenmortel, M. H. V., Fauquet, C. M., Bishop, D. H. L., Calisher, C. H., Carsten, E. B., Estes, M. K., Lemon, S. M., Maniloff, J., Mayo, M. A., McGeogh, D. J., Pringle, C. R., Winckner, R. B. New York, San Diego: Academic Press, 2003, 657 – 673.

5. Klingel, K., Stephan, S., Sauter, M., Zell, D., McManus, B., Bultmann, B., Kandolf, R. Pathogenesis of murine enterovirus myocarditis: virus dissemination and immune cell targets. J Virol, 1996, 70, 8888 – 8895.

6. Muir, P., Nicholson, F., Tilzey, A. J., Signy, M., English, T. A. H., Banatvala, J. E. Chronic relapsing pericarditis and dilated cardiomyopathy: Serological evidence of persistent enterovirus infection. Lancet, 1989, 1, 804 – 807.

7. Racaniello, V. R. Picornaviridae: The viruses and their replication. In Knipe, D. M., Howley, P. M., Griffin, D. E., Lamb, R. A., Martin, M. A., Riozman, B., Straus S. E. (eds.) Fields Virology, 4th ed., Vol. 1, Lippincott Philadelphia: Williams and Wilkins, 2001, 685 – 722.

8. Petrovičová, A., Bopegamage, S., Barák, Ľ., Egnerová, A. 20-ročné sledovanie markerov coxsackievírusovej infekcie v rôznych skupinách detí. Správy klinickej mikrobiológie, 2006, 3, 73.

9. Parks, W. P., Queiroga, L. T., Melnick J. L. Studies of infantile diarrhea in Karachi, Pakistan. II. Multiple virus isolations from rectal swabs, Am J Epid, 1967, 85, 469 – 478.

10. Tracy, S., Drescher, K. M., Chapman, N. M., Kim,K. S., Carson, S. D., Pirruccello, S. S., Lane, P. H., Romero, J. R., Leser J. S. Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence. J Virology, 2002, 76, 12097 – 12111.

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