The occurrence of developmental enamel defects in very low and extremely low birth-weight infants
Authors:
V. Merglová 1; R. Koberová Ivančaková 2; J. Dort 3
Authors‘ workplace:
Stomatologická klinika, Lékařská fakulta Univerzity Karlovy a Fakultní nemocnice, Plzeň
1; Stomatologická klinika, Lékařská fakulta Univerzity Karlovy a Fakultní nemocnice, Hradec Králové
2; Neonatologické oddělení, Fakultní nemocnice, Plzeň
3
Published in:
Česká stomatologie / Praktické zubní lékařství, ročník 119, 2019, 1, s. 18-25
Category:
Original articles
Overview
Introduction, aim: Preterm infants with very low birt-weights (VLBW) and extremely low birth-weights (ELBW) suffer from several prenatal and neonatal complications and morbidity that may affect mineralization of primary teeth and occurrence of developmental defects of enamel (DDE). The aim of the study was to establish relationship between gen-der of infant, gestational age, birth-weight and frequency of laryngoscopies and occurrence of DDE in primary incisors in preterm one-year-old infants delivered with very low birth-weight and extremely low birth-weight.
Methods: The case-control study was realized in 132 one-year-old preterm infants delivered with VLBW and ELBW and data were compared with 58 physiological birth-
weight full term infants. The data were obtained from hospital records, from interview with mothers and from intraoral examination of infants. The data were statistically analysed using χ2 test and multifactorial logistic regression analysis in order to find possible risk factors associated with the occurrence of DDE. The statistical significance level p < 0.05 was established.
Results: The case cohort (A) consists of 62 boys (47%) and 70 girls (53%) with mean gestational age 28.8 weeks and mean birth-weight 1119.7 g. The controls (B) were 24 girls (34.5%) and 34 boys (65.5%) with mean gestational age 39.6 weeks and mean birth-weight 3418,6 g. ELBW was associated with DDE in primary incisors (p = 0.009). DDE were more frequent in boys (p = 0.054) and in infants with low gestational age (p = 0.22) but no significant statistical relationship was found. Concerning the possible local cause of DDE, this study has found that infants with higher frequency of laryngoscopies showed a higher prevalence of DDE (p = 0.053) but no statistical relationship was found.
Conclusion: Various local and systemic factors of DDE act probably together and therefore it is very difficult to identify the aetiological factor strongly related to DDE.
Keywords:
very low birth-weight infant – extremely low birth-weight infant – preterm infant – enamel hypoplasia – enamel opacities – laryngoscopy
Sources
1. World Health Organization.International classification of diseases and related health problems, 10th revision. Geneva: World Health Organization; 2004.
2. Soewondo W, Effendi SH.The incidence of enamel hypoplasia and hypocalcification in low birth weight children according to teeth type. J Dent. 2012; 2(3): 200–205.
3. Dort J, Dortová E.Nejčastější problémy novorozence s velmi nízkou porodní hmotností v péči PLDD. Pediatr Praxi. 2011; 12(3): 171–176.
4. Bansal R, Bansal R, Sharma A, Sidram G.Effect of low birth weight and very low birth weight on primary dentition in the Indian population. Internet J Pediatr Neonatol. 2012; 14(2).
5. Aminabadi NA, Farahani RMZ, Gajan EB.Apgar index as a correlate of enamel defects of primary dentition. Oral Health Prev Dent. 2008; 6(4): 331–335.
6. Angelos GM, Smith DR, Jorgenson R, Sweeney EA.Oral complications associated with neonatal oral tracheal intubation: a critical review. Pediatr Dent. 1989; 11(2): 133–140.
7. Jacobsen PE, Haubek D, Henriksen TB, Østergaard JR, Poulsen S.Developmental enamel defects in children born preterm: a systematic review. Eur J Oral Sci. 2014; 122(1): 7–14.
8. Salanitri S, Seow WK.Developmental enamel defects in the primary dentition: aetiology and clinical management. Aust Dent J. 2013; 58(2): 133–140.
9. Velló MA, Martínez-Costa C, Catalá M, Fons J, Brines J, Guijarro-Martínez R.Prenatal and neonatal risk factors forthe development of enamel defects in low birth weight children. Oral Dis. 2010; 16(3): 257–262.
10. FDI Commission on Oral Health, Research and Epidemiology (1992).A review of developmental defects of enamel index (DDE index). Int Dent J. 1992; 42(6): 411–426.
11. Memarpour M, Golkari A, Ahmadian R.Association of characteristics of delivery and medical conditions during the first month of life with developmental defects of enamel. BMC Oral Health 2014, 14, p. 122. http://www.biomedcentral.com/1472-6831/14/122.
12. Fearne JM, Bryan EM, Elliman AM, Brook AH, Williams DM.Enamel defects in the primary dentition of children born weighing less than 2000g. Br Dent J. 1990; 168(11): 433–437.
13. Johnsen D, Krejci C, Hack M, Fanaroff A.Distribution of enamel defects and the association with respiratory distress in very low birthweight infants. J Dent Res. 1984; 63(1): 59–64.
14. Lin X, Wu W, Zhang Ch, Lo ECM, Chu CH, Dissanayaka WL. Prevalence and distribution of developmental enamel defects in children with cerebral palsy in Beijing, China. Int J Paediatr Dent. 2010; 21(1): 23–28.
15. Norén JG, Ranggård L, Klinberg G, Person C, Nilsson K. Intubation and mineralization disturbances in the enamel of primary teeth. Acta Odontol Scand. 1993; 51(3): 271–275.
16. Seow WK, Brown JP, Tudehop DA, O´Callaghan M.Dental defects in the deciduous dentition of premature infants with low birth weight and neonatal rickets. Pediatr Dent. 1984; 6(2): 88–92.
17. Seow WK, Brown JP, Tudehope DI, O´Callaghan M.Developmental defects in the primary dentition of low birth-weight infants: adverse effects of laryngoscopy and prolonged endotracheal intubation. Pediatr Dent. 1984; 6(1): 28–31.
18. Seow WK, Masel JP, Weir C, Tudehope, DI.Mineral deficiency in the pathogenesis of enamel hypoplasia in prematurely born, very low birthweight children.Pediatr Dent. 1989; 11(4): 297–302.
19. Hong L, Levy SM, Warren JJ, Dawson DV, Bergus GR, Wefel JS.Association of amoxicillin use during early childhood with developmental tooth enamel defects. Arch Pediatr Adolesc Med. 2005; 159(10): 943–948.
20. Franco KMD, Line SRP, de Moura-Ribeiro MVL.Prenatal and neonatal variables associated with enamel hypoplasia in deciduous teeth in low birth weight infants. J Appl Oral Sci. 2007; 15(6): 518–523.
21. Lai PY, Seow WK, Tudehope DI, Rogers Y.Enamel hypoplasia and dental caries in very-low birthweight children: a case-controlled, longitudinal study. Pediatr Dent. 1997; 19(1): 42–49.
22. Nelson S, Albert JM, Geng O, Cuman S, Lang K, Madich S, Heima M, Malik A, Feneth G, Eqqersston H, Stayton RL, Milgrom P.Increased enamel hypoplasia and very low birthweight infants. J Dent Res. 2013; 92(9): 788–794.
23. Seow WK, Humphrys C, Tudehope DI.Increased prevalence of developmental dental defects in low birth-weight, prematurely born children: a controlled study. Pediatr Dent. 1987; 9(3): 221–225.
24. Pimlott JFL, Howley TP, Nikiforuk G, Fitzhardinge PM.Enamel defects in prematurely born, low birth-weight infants. Pediatr Dent. 1985; 7(3): 218–223.
25. Cruvinel VRN, Gravina DBL, Azevedo TDPL, de Rezende CS, Bezerra ACB, de Toledo OA.Prevalence of enamel defects and associated risk factors in both dentitions in preterm and full term born children. J Appl Oral Sci. 2012; 20(3): 310–317.
26. Aine L, Backström MC, Mäki R, Kuusela AL, Koivisto AM, Ikonen RS, Mäki M.Enamel defects in primary and permanent teeth of children born prematurely. J Oral Pathol Med. 2000; 29(8): 403–409.
27. Corrê-Faria P, Martins-Júnior PA, Vieira-Andrade RG, Oliveira-Fereira F, Marques LS, Ramos-Jorge ML.Developmental defects of enamel in primary teeth: prevalence and associated factors. Int J Paed Dent. 2013; 23(3): 173–179.
28. Pinho JRO, Filho FM, Thomaz EBAF, Lamy ZC, Libério SA, Ferreira EB.Are low birth weight, intrauterine growth restriction, and preterm birth associated with enamel developmental defects? Pediatr Dent. 2012; 34(3): 244–245.
29. Matsumoto T, Cavalho WB.Tracheal intubation. J Pediatr. 2007; 83(2): 83–90.
Labels
Maxillofacial surgery Orthodontics Dental medicineArticle was published in
Czech Dental Journal
2019 Issue 1
Most read in this issue
- Pharmacotherapy of recurrent aphthous stomatitis in patients with genetically impaired ability to metabolize folic acid – pilot study
- The occurrence of developmental enamel defects in very low and extremely low birth-weight infants
- Methods used for facial morphology research