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Inclisiran: the first siRNA approved by European Medicines Agency for treatment of dyslipidemias


Authors: Michal Vrablík
Authors‘ workplace: Centrum preventivní kardiologie, III. interní klinika – klinika endokrinologie a metabolismu 1. LF UK a VFN v Praze
Published in: AtheroRev 2021; 6(1): 50-51
Category:


Sources
  1. Ray KK, Wright RS, Kallend D. [ORION-10 and ORION-11 Investigators]. Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol. N Engl J Med 2020; 382(16): 1507–1519. Dostupné z DOI: <http://doi: 10.1056/NEJMoa1912387>.

  2. Raal FJ, Kallend D, Ray KK. [ORION-9 Investigators]. Inclisiran for the Treatment of Heterozygous Familial Hypercholesterolemia. N Engl J Med 2020; 382(16): 1520–1530. Dostupné z DOI: <http://doi: 10.1056/NEJMoa1913805>.

  3. Informace dostupné z WWW: <https://www.ema.europa.eu/en/medicines/human/EPAR/leqvio>.

Labels
Angiology Diabetology Internal medicine Cardiology General practitioner for adults

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Athero Review

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2021 Issue 1

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