Fate of Recipients of Cadaveric Organ from Donors with a CNS Tumor

Czech version

Authors: E. Pokorná; Š. Vítko
Authors‘ workplace: Transplantcentrum, Institut klinické a experimentální medicíny, Praha, přednosta MUDr. Štefan Vítko
Published in: Anest. intenziv. Med., , 2001, č. 4, s. 213-215
Category:

Overview

ntroduction:
We conducted a retrospective study designed to monitor the fate of recipients of organs from donors with a CNS tumor to establishwhether or not the malignancy got transferred.Material and methods: A total of 2,048 cadaveric organ donors were indicated for organ harvesting in the Czech Republic in the 1986–1998 period;in 42 (2.1%), the cause of the brain death was a CNS tumor. In one case, autopsy showed metastasis of bronchogenic carcinoma so the diagnosis ofa CNS tumor was erroneous! A total of 92 organs (79 kidneys, 4 hearts, 5 livers, 3 pancreases, and 1 lung) were transplanted to 89 recipients.Results: Six recipients died immediately after transplantation, eleven recipients died in the late post-transplant period; of this number, two died dueto malignancy (generalization of gynaecological carcinoma and bronchogenic carcinoma).Conclusion: In a group of 42 donors with the diagnosis of a CNS tumor, no malignancy transmission was demonstrated in 89 recipients.

Key words:
cadaveric organ donor - CNS tumor - malignancy transmission

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