PLOS Genetics - Číslo 4/2012

Review

32767

Modifier Genes and the Plasticity of Genetic Networks in Mice

Defective Membrane Remodeling in Neuromuscular Diseases: Insights from Animal Models

Research Article

32767

Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor

The DSIF Subunits Spt4 and Spt5 Have Distinct Roles at Various Phases of Immunoglobulin Class Switch Recombination

A Genome-Wide Screen for Genetic Variants That Modify the Recruitment of REST to Its Target Genes

Population Structure of Hispanics in the United States: The Multi-Ethnic Study of Atherosclerosis

Deep Sequencing of Plant and Animal DNA Contained within Traditional Chinese Medicines Reveals Legality Issues and Health Safety Concerns

Differing Requirements for RAD51 and DMC1 in Meiotic Pairing of Centromeres and Chromosome Arms in

Insulin Signaling Mediates Sexual Attractiveness in

Progressive Telomere Dysfunction Causes Cytokinesis Failure and Leads to the Accumulation of Polyploid Cells

Long-Range Chromosome Organization in : A Site-Specific System Isolates the Ter Macrodomain

Regulation of Budding Yeast Mating-Type Switching Donor Preference by the FHA Domain of Fkh1

Polyglutamine Toxicity Is Controlled by Prion Composition and Gene Dosage in Yeast

Patterns of Regulatory Variation in Diverse Human Populations

Sequence-Specific Targeting of Dosage Compensation in Favors an Active Chromatin Context

Whole-Exome Sequencing and Homozygosity Analysis Implicate Depolarization-Regulated Neuronal Genes in Autism

Replication Fork Reversal after Replication–Transcription Collision

Common Variants at 9p21 and 8q22 Are Associated with Increased Susceptibility to Optic Nerve Degeneration in Glaucoma

Coordinate Regulation of Lipid Metabolism by Novel Nuclear Receptor Partnerships

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population

A Coordinated Interdependent Protein Circuitry Stabilizes the Kinetochore Ensemble to Protect CENP-A in the Human Pathogenic Yeast

Budding Yeast Dma Proteins Control Septin Dynamics and the Spindle Position Checkpoint by Promoting the Recruitment of the Elm1 Kinase to the Bud Neck

, a Homolog of a Deaf-Blindness Gene, Regulates Circadian Output and Slowpoke Channels

Transcriptional Regulation of Rod Photoreceptor Homeostasis Revealed by NRL Targetome Analysis

Cell Contact–Dependent Outer Membrane Exchange in Myxobacteria: Genetic Determinants and Mechanism

Formation of Rigid, Non-Flight Forewings (Elytra) of a Beetle Requires Two Major Cuticular Proteins

SPE-44 Implements Sperm Cell Fate

A Shared Role for RBF1 and dCAP-D3 in the Regulation of Transcription with Consequences for Innate Immunity

A Companion Cell–Dominant and Developmentally Regulated H3K4 Demethylase Controls Flowering Time in via the Repression of Expression

The HEN1 Ortholog, HENN-1, Methylates and Stabilizes Select Subclasses of Germline Small RNAs

Improved Statistics for Genome-Wide Interaction Analysis

The Probability of a Gene Tree Topology within a Phylogenetic Network with Applications to Hybridization Detection

Context-Dependent Dual Role of SKI8 Homologs in mRNA Synthesis and Turnover

Mu Insertions Are Repaired by the Double-Strand Break Repair Pathway of

Competition between Replicative and Translesion Polymerases during Homologous Recombination Repair in Drosophila

An Unbiased Assessment of the Role of Imprinted Genes in an Intergenerational Model of Developmental Programming

Type 2 Diabetes Risk Alleles Demonstrate Extreme Directional Differentiation among Human Populations, Compared to Other Diseases

Mutations in and Cause “Splashed White” and Other White Spotting Phenotypes in Horses

Fine-Scale Mapping of Natural Variation in Fly Fecundity Identifies Neuronal Domain of Expression and Function of an Aquaporin

Dynamics of Brassinosteroid Response Modulated by Negative Regulator LIC in Rice

Genetic Inhibition of Solute-Linked Carrier 39 Family Transporter 1 Ameliorates Aβ Pathology in a Model of Alzheimer's Disease

The Functions of Mediator in Support a Role in Shaping Species-Specific Gene Expression

Patterns of Ancestry, Signatures of Natural Selection, and Genetic Association with Stature in Western African Pygmies

Dissection of Pol II Trigger Loop Function and Pol II Activity–Dependent Control of Start Site Selection

PIWI Associated siRNAs and piRNAs Specifically Require the HEN1 Ortholog

Genome-Wide Patterns of Gene Expression in Nature

Hypoxia Disruption of Vertebrate CNS Pathfinding through EphrinB2 Is Rescued by Magnesium

A New Role for Translation Initiation Factor 2 in Maintaining Genome Integrity

Sex Reversal in C57BL/6J XY Mice Caused by Increased Expression of Ovarian Genes and Insufficient Activation of the Testis Determining Pathway

The Rac GTP Exchange Factor TIAM-1 Acts with CDC-42 and the Guidance Receptor UNC-40/DCC in Neuronal Protrusion and Axon Guidance

PLOS Genetics

2012 Číslo 4

Nejčtenější v tomto čísle