Outpatient parenteral antibiotic therapy (OPAT)
Authors:
MUDr. Marek Štefan; prof. MUDr. Ph.D. Michal Holub
Authors‘ workplace:
Klinika infekčních nemocí 1. LF UK a ÚVN-VFN Praha
Published in:
Čas. Lék. čes. 2016; 155: 131-134
Category:
Review Article
Overview
Traditionally, parenteral (i. e. intravenous) antimicrobial therapy has been used in inpatients with various bacterial infections. In recent decades there has been growing experience with outpatient parenteral antimicrobial therapy, mainly in the USA and western Europe. This article provides basic information on OPAT, based on available literature and the author´s experience on running OPAT service in the UK.
Keywords:
ambulatory care, intravenous antibiotics, cellulitis, bone and joint infection
Sources
1. Rucker RW, Harrison GM. Outpatient intravenous medications in the management of cystic fibrosis. Pediatrics 1974; 54: 358−360.
2. Seaton RA, Barr DA. Outpatient parenteral antibiotic therapy: Principles and practice. Eur J Inter Med 2013; 24: 617−623.
3. Chapman AL. Outpatient parenteral antimicrobial therapy. BMJ 2013; 346: f1585.
4. Tice AD, Rehm SJ, Dalovisio JR et al. Practice guidelines for outpatient parenteral antimicrobial therapy. IDSA guidelines. Clin Infect Dis 2004; 38: 1651−1672.
5. Ho J et al. Safe and successful treatment of intravenous drug users with a peripherally inserted central catheter in an outpatient parenteral antibiotic treatment service. J Antimicrob Chemother 2010; 65: 2641−2644.
6. Barr DA, Seaton RA. Outpatient parenteral antimicrobial therapy (OPAT) and the general physician. Clin Med 2013; 13: 495−499.
7. Barr DA et al. OPAT in a teaching hospital-based practice: a retrospective cohort study describing experience and evolution over 10 years. Int J Antimicrob Agents 2012; 39: 407−413.
Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental HygienistArticle was published in
Journal of Czech Physicians
Most read in this issue
- Vesicoureteric reflux in children: many questions still unanswered
- Surgical treatment of lower extremity peripheral nerve injuries
- Faecal incontinence – serious medical and social issue
- Hyponatremia in children: from pathophysiology to therapy