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Granulocyte Colony Stimulating Factor in the Treatment of Severe Neutropenia in Very LowBirth Weight Neonates


Authors: Z. Straňák 1,2;  S. Bělohlávková;  J. Melichar;  J. Janota;  J. Kučera;  J. Šimák 1
Authors‘ workplace: Ústav pro péči o matku a dítě, Praha 1
Published in: Čes-slov Pediat 2000; (4): 227-229.
Category:

Overview

The granulocyte-colony stimulating factor (G-CSF) was used in two extremely low birth weight infants withsevere neutropenia where sepsis was not confirmed. During 12 hours after the initial dose of 5 mg/kg/day of G-CSF(Granocyte 13, Rhone Poulenc) in combination with dexamethasone, a significant rise of the absolute neutrophilcount occurred and remained in the normal range. No side-effects were observed during the course of therapy.We suppose that G-CSF may be used in indicated cases of severe neutropenia in extremely premature newborns.

Key words:
extremely premature newborn, neutropenia, granulocyte-colony stimulati ng factor

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Labels
Neonatology Paediatrics General practitioner for children and adolescents

Article was published in

Czech-Slovak Pediatrics


2000 Issue 4

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