PLOS Genetics - Číslo 7/2015

Perspective

32767

LINE-1 Retroelements Get ZAPped!

/p23: A Small Protein Heating Up Lifespan Regulation

Interview

32767

Irrepressible: An Interview with Mark Ptashne

Research Article

32767

Hairless Streaks in Cattle Implicate TSR2 in Early Hair Follicle Formation

Ribosomal Protein Mutations Result in Constitutive p53 Protein Degradation through Impairment of the AKT Pathway

Molecular Clock of Neutral Mutations in a Fitness-Increasing Evolutionary Process

Modeling Implicates in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress

The Alternative Sigma Factor SigX Controls Bacteriocin Synthesis and Competence, the Two Quorum Sensing Regulated Traits in

BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma

Comparative Study of Regulatory Circuits in Two Sea Urchin Species Reveals Tight Control of Timing and High Conservation of Expression Dynamics

EIN3 and ORE1 Accelerate Degreening during Ethylene-Mediated Leaf Senescence by Directly Activating Chlorophyll Catabolic Genes in

Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins

Sensory Neurons Arouse . Locomotion via Both Glutamate and Neuropeptide Release

A Year of Infection in the Intensive Care Unit: Prospective Whole Genome Sequencing of Bacterial Clinical Isolates Reveals Cryptic Transmissions and Novel Microbiota

Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer

Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

A Novel Locus Harbouring a Functional Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment

Checkpoint Activation of an Unconventional DNA Replication Program in

A Genetic Incompatibility Accelerates Adaptation in Yeast

The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity

Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

JAK/STAT and Hox Dynamic Interactions in an Organogenetic Gene Cascade

Emergence, Retention and Selection: A Trilogy of Origination for Functional Proteins from Ancestral LncRNAs in Primates

MoSET1 (Histone H3K4 Methyltransferase in ) Regulates Global Gene Expression during Infection-Related Morphogenesis

Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers

AAA-ATPase FIDGETIN-LIKE 1 and Helicase FANCM Antagonize Meiotic Crossovers by Distinct Mechanisms

A Conserved Pattern of Primer-Dependent Transcription Initiation in and Revealed by 5′ RNA-seq

Tempo and Mode of Transposable Element Activity in Drosophila

The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres

SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation

A Genome Scan for Genes Underlying Microgeographic-Scale Local Adaptation in a Wild Species

TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis

Analysis of the Relationships between DNA Double-Strand Breaks, Synaptonemal Complex and Crossovers Using the Mutant

Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools

Allelic Spectra of Risk SNPs Are Different for Environment/Lifestyle Dependent versus Independent Diseases

CSB-PGBD3 Mutations Cause Premature Ovarian Failure

Genetic Evidence for Function of the bHLH-PAS Protein Gce/Met As a Juvenile Hormone Receptor

Inactivation of Retinoblastoma Protein (Rb1) in the Oocyte: Evidence That Dysregulated Follicle Growth Drives Ovarian Teratoma Formation in Mice

Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis

Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA

Molecular Framework of a Regulatory Circuit Initiating Two-Dimensional Spatial Patterning of Stomatal Lineage

RFX2 Is a Major Transcriptional Regulator of Spermiogenesis

A Role for Macro-ER-Phagy in ER Quality Control

Corp Regulates P53 in via a Negative Feedback Loop

Common Cell Shape Evolution of Two Nasopharyngeal Pathogens

Contact- and Protein Transfer-Dependent Stimulation of Assembly of the Gliding Motility Machinery in

Endothelial Snail Regulates Capillary Branching Morphogenesis via Vascular Endothelial Growth Factor Receptor 3 Expression

Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality

Temporal Coordination of Carbohydrate Metabolism during Mosquito Reproduction

mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis

Reversible Oxidation of a Conserved Methionine in the Nuclear Export Sequence Determines Subcellular Distribution and Activity of the Fungal Nitrate Regulator NirA

Nutritional Control of DNA Replication Initiation through the Proteolysis and Regulated Translation of DnaA

Cooperation between Paxillin-like Protein Pxl1 and Glucan Synthase Bgs1 Is Essential for Actomyosin Ring Stability and Septum Formation in Fission Yeast

Encodes a Highly Conserved Protein Important to Neurological Function in Mice and Flies

Identification of a Novel Regulatory Mechanism of Nutrient Transport Controlled by TORC1-Npr1-Amu1/Par32

Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly

Large-Scale Phenomics Identifies Primary and Fine-Tuning Roles for CRKs in Responses Related to Oxidative Stress

TFIIS-Dependent Non-coding Transcription Regulates Developmental Genome Rearrangements

Genome-Wide Reprogramming of Transcript Architecture by Temperature Specifies the Developmental States of the Human Pathogen

Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish

The Catalytic and Non-catalytic Functions of the Chromatin-Remodeling Protein Collaborate to Fine-Tune Circadian Transcription in

PLOS Genetics

2015 Číslo 7

Nejčtenější v tomto čísle