Atypical course of typical lung carcinoid

Česká verze

Authors: L. Jakubíková
Authors place of work: Klinika nemocí plicních a tuberkulózy, FN Brno
Published in the journal: Klin Onkol 2020; 33(4): 302-308
Category: Kazuistika
doi: https://doi.org/10.14735/amko2020302

Summary

Carcinoids have been classified according to their embryonic origin in the past and are now categorized and classified as neuroendocrine tumors, including low malignant typical carcinoids, moderate malignant atypical carcinoids, and highly malignant large cell neuroendocrine and small cell carcinomas. A typical carcinoid is a previously used term for the current designation of a grade I neuroendocrine tumor, well differentiated, belonging to a group of rare tumors with a good prognosis with metastasis of less than 15% with a five-year survival of more than 90%, rarely producing serotonin. Even this biologically favorable tumor with a relatively low degree of metastasis cannot be underestimated.

Case: The following section summarizes the classification of neuroendocrine tumors, their diagnosis and treatment, and the second section presents a specific case of a patient with multiple metastases of an original lung carcinoid (histology at the time of surgery 2012, at the time of using this older version of neuroendocrine tumors) describing its further treatment.

Conclusion: In well differentiated neuroendocrine tumors, there is a significant risk of metastasis despite their radical surgery; their dispensarization is therefore necessary.

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE recommendation for biomedical papers.

Keywords:

everolimus – neuroendocrine neoplasm – octreotide

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