#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

Vaginal application of estradiol in women with urogenital atrophy – important influence on the quality of life


Authors: MUDr. Jiří Kepák, CSc.
Authors‘ workplace: Gynekologické pracoviště, Úrazová nemocnice, Brno
Published in: Prakt Gyn 2005; 9(1): 20-21

Overview

The women spend more than one third of their lives in the condition of postmenopausal estrogen defficiency. It leads to the changes in lower urinary tract and vagina, which have a negative influence on the quality of life. The symptoms of urogenital atrophic discomfort are common and subjectively stressing. They can be moderated by appropriate exogenous estrogen substitution. The number of women suffering from unpleasant subjective symptoms in consequence of local estrogen defficiency disease (colpoxerosis, pruritus, dyspareunia, dysuria, urgent urination, urgent urinary incontinence) is higher than it is generally presumed. Urogenital atrophy prevalence is growing to 40–45 % after menopause. With the population ageing expected, the number of women with these problems will still increase. There are many women who need local vaginal estrogenization which would be comfortably applicable, hygienically acceptable, acting with any side effects or possible risks. It is therefore necessary to make them an active offer of a proved, nonloading and at the same time an effective way how to moderate everyday urogenital discomfort. Own practical experience with the treatment of significant subjective urogynaecologic complaints includes 42 postmenopausal patients in the age of 45–79 years (average age 65,1 years). There had been used a substitution local therapy with low 17-beta estradiol (VAGIFEM tbl vag). At the continuous controls, 36 patients (85,4%) had subjectively felt cured or significantly improved. Local application of estradiol significantly improves the quality of life of menopausal women. To achieve optimal results, a long-term treatment is required. The improvement of quality of life as a subjective feeling is crucial.

Key words:
quality of life during menopause – estrogen deficiency disease – urogenital discomfort – local estradiol therapy


Sources

1. Šimunić V, Banović I, Ciglar S et al. Local estrogen treatment in patients with urogenital symptoms. Int J Obstet Gynecol 2003; 82: 187-197.

2. Berman JR, Berman L, Goldstein I. Female sexual dysfunction: Incidence, pathophysiology, evaluation, and options. Urol 1999; 54: 385-391.

3. Notelovitz M. Editorial: urogenital atrophy and low-dose vaginal estrogen therapy. Menopause 2000; 7: 140-142.

4. Huvar I. Kvalita života při močové inkontinenci. Prakt Gyn 2003; 1: 18-22.

5. Chmel R, Rob L, Vlk R et al. Prevalence ženské močové inkontinence. Výsledky dotazníkové studie. Čes Gynek 2004; 3: 339-344.

6. Donát J. Postmenopauza - estrogenní deficit v klinické praxi. Praha: DoMeNa 2003.

7. Jeníček J. Současná indikace HRT – kvalita života. Prakt Gyn 2003; 2: 28.

8. Hejlová P, Zmrhal J. Vliv estrogenu na dolní cesty močové. Prakt Gyn 2002; 4: 26-28.

9. Čepický P. Chronické a recidivující vulvovaginitidy. Prakt Gyn 2004; 2: 8-9.

10. Sarrell PM. Sexuality and menopause. Obstet Gynecol 1990; 75: 26a.

11. Koliba P, Koliba M, Dančíková Z. Sexuální život žen po menopauze. Klimakter Med 2003; 3: 11-12.

12. Hejlová P, Živný J. Vliv vaginálního estriolu na urogenitální symptomy u postmenopauzálních žen. Čes Gynek 2004; 4: 329-335.

13. Fait T. Zpráva z kongresu: Zdraví žen a menopauza. Prakt Gyn 2004; 4: 58-60.

14. Fait T. Zpráva z kongresu: Zdraví žen po WHI – 4. amsterodamské menopauzální sympozium. Prakt Gyn 2004; 6: 43-45.

15. Rioux JE, Devlin MC, Gelfand MM et al. 17β-Estradiol vaginal tablet versus conjugated equine estrogen vaginal cream to relieve menopausal atrophic vaginitis. Menopause 2000; 7: 156-161.

16. Drahorádová P, Martan A, Mašata J et al. Kvalita života žen po urogynekologických operacích. Čes Gynek 2003; 4: 243-249.

Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicine
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#