Neuroendocrine tumor of the periappendicular area of the cecum bottom – a case report
Authors:
Bača L. 1; Psár R. 2,3; Hanousek M. 1; Fojtík P. 1
Authors‘ workplace:
Centrum péče o zažívací trakt, Nemocnice AGEL Ostrava-Vítkovice a. s.
1; Radiologické oddělení, Nemocnice AGEL Ostrava-Vítkovice a. s.
2; Lékařská fakulta Univerzity Palackého v Olomouci
3
Published in:
Gastroent Hepatol 2021; 75(1): 68-71
Category:
Gastrointestinal Oncology: Case Report
doi:
https://doi.org/10.48095/ccgh202168
Overview
Neuroendocrine tumors are slow-growing neoplasms, histologically based on enteroendocrine cells. They are tumors with different degrees of differentiation, uncertain biological nature and metastatic ability. Their most common localization is the gastrointestinal tract, with a special group of the neuroendocrine tumors of appendix, which are incidentally found after appendectomy. In case report, we would like to present a case of a patient with neuroendocrine tumors of appendix diagnosed by colonoscopy.
Keywords:
neuroendocrine tumor – appendix – colonoscopy
Sources
1. Connor SJ, Hanna GB, Frizelle FA. Appendiceal tumors: retrospective clinicopathologic analysis of appendiceal tumors from 7,970 appendectomies. Dis Colon Rectum 1998; 41(1): 75–80. doi: 10.1007/ BF02236899.
2. Unver N, Coban G, Arıcı DS et al. Unusual Histopathological Findings in Appendectomy Specimens: A Retrospective Analysis of 2047 Cases. Int J Surg Pathol 2019; 27(2): 142–146. doi: 10.1177/ 1066896918784650.
3. Sandor A, Modlin IM. A retrospective analysis of 1570 appendiceal carcinoids. Am J Gastroenterol 1998; 93(3): 422–428. doi: 10.1111/ j.1572-0241.1998.00422.x.
4. Mullen JT, Savarese DM. Carcinoid tumors of the appendix: a population-based study. J Surg Oncol 2011; 104(1): 41–44. doi: 10.1002/ jso. 21888.
5. Goede AC, Caplin ME, Winslet MC. Carcinoid tumour of the appendix. Br J Surg 2003; 90(11): 1317–1322. doi: 10.1002/ bjs.4375.
6. Pape UF, Niederle B, Costa F et al. ENETS Consensus Guidelines for Neuroendocrine Neoplasms of the Appendix (Excluding Goblet Cell Carcinomas). Neuroendocrinology 2016; 103(2): 144–152. doi: 10.1159/ 000443165.
7. Dasari A, Shen C, Halperin D et al. Trends in the Incidence, Prevalence, and Survival Outcomes in Patients with Neuroendocrine Tumors in the United States. JAMA Oncol 2017; 3(10): 1335–1342. doi: 10.1001/ jamaoncol.2017.0589.
8. Maggard MA, O‘Connell JB, Ko CY. Updated population-based review of carcinoid tumors. Ann Surg 2004; 240(1): 117–122. doi: 10.1097/ 01.sla.0000129342.67174.67.
9. Ellis L, Shale MJ, Coleman MP. Carcinoid tumors of the gastrointestinal tract: trends in incidence in England since 1971. Am J Gastroenterol 2010; 105(12): 2563–2369. doi: 10.1038/ ajg. 2010.341.
10. Klimstra DS, Kloppell G, La Rosa S et al. Classification of neuroendocrine neoplasms of the digestive system. In: WHO Classification of Tumours: Digestive System Tumours. 5th ed. Lyon: International Agency for Research on Cancer 2019: 16.
11. Hsu C, Rashid A, Xing Y et al. Varying malignant potential of appendiceal neuroendocrine tumors: importance of histologic subtype. J Surg Oncol 2013; 107(2): 136–143. doi: 10.1002/ jso.23205.
12. Cai W, Tan Y, Ge W et al. Pattern and risk factors for distant metastases in gastrointestinal neuroendocrine neoplasms: a population-based study. Cancer Med 2018; 7(6): 2699–2709. doi: 10.1002/ cam4.1507.
13. Goede AC, Caplin ME, Winslet MC: Carcinoid tumour of the appendix. Br J Surg 2003; 90(11): 1317–1322. doi: 10.1002/ bjs.4375.
14. Groth SS, Virnig BA, Al-Refaie WB et al. Appendiceal carcinoid tumors: predictors of lymph node metastasis and the impact of right hemicolectomy on survival. J Surg Oncol 2011; 103(1): 39–45. doi: 10.1002/ jso.21764.
15. Stinner B, Rothmund M: Neuroendocrine tumours (carcinoids) of the appendix. Best Pract Res Clin Gastroenterol 2005; 19(5): 729–738. doi: 10.1016/ j.bpg.2005.06.003.
16. Šachlová M. Neuroendokrinní nádory v gastroenterologické praxi. Gastroent Hepatol 2016; 70(3); 220–225. doi:10.14735/ amgh2016csgh.info04.
17. O’Toole D, Grossman A, Gross D et al. ENETS consensus guidelines for the standards of care in neuroendocrine tumors: biochemical markers. Neuroendocrinology 2009; 90(2): 194–202. doi: 10.1159/ 000225948.
18. Pape UF, Perren A, Niederle B et al. ENETS consensus guidelines for the management of patients with neuroendocrine neoplasms from the jejuno-ileum and the appendix including goblet cell carcinomas. Neuroendocrinology 2012; 95(2): 135–156. doi: 10.1159/ 000335629.
19. Louthan O. Neuroendokrinní tumory appendixu. Vnitř Lék 2009; 55 (11): 1051–1055.
20. Louthan O. Neuroendokrinní tumory tenkého střeva – jejuna a ilea. Čes a Slov Gastroent a Hepatol 2009; 63(6): 284–291.
14. Landry CS, Woodall C, Scoggins CR et al. Analysis of 900 appendiceal carcinoid tumors for a proposed predictive staging system. Arch Surg 2008; 143(7): 664–670. doi: 10.1001/ archsurg. 143.7.664.
21. Virgone C, Cecchetto G, Alaggio A et al. Appendiceal neuroendocrine tumours in child- hood: Italian TREP project. J Pediatr Gastroenterol Nutr 2014; 58(3): 333–338. doi: 10.1097/ MPG.0000000000000217.
23. Boudreaux JP, Klimstra DS, Hassan MM et al. The NANETS consensus guideline for the diagnosis and management of neuroendocrine tumors: well-differentiated neuroendocrine tumors of the Jejunum, Ileum, Appendix, and Cecum. Pancreas 2010; 39(6): 753–766.
24. Kunz PL, Reidy-Lagunes D, Anthony LB et al. Consensus guidelines for the management and treatment of neuroendocrine tumors. Pancreas 2013; 42(4): 557–577. doi: 10.1097/ MPA. 0b013e31828e34a4.
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Paediatric gastroenterology Gastroenterology and hepatology SurgeryArticle was published in
Gastroenterology and Hepatology
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