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A solitary skeletal metastasis in the thumb of a silent bilateral clear cell renal cell carcinoma pT1a in a patient with a sporadic uro‑oncological triplicity


Authors: Jan Novák 1;  Lukáš Fišer 1;  Robert Jůzek 2;  Jan Lesenský 2;  Jan Pertlíček 3;  Zuzana Špůrková 4;  Petra Beroušková 5;  Lubomír Hyršl 1
Authors‘ workplace: Urologické oddělení, Oblastní nemocnice Kladno, a. s., Kladno 1;  Ortopedická klinika, 1. LF UK a Nemocnice Na Bulovce, Praha 2;  Chirurgické oddělení, Oblastní nemocnice Kladno, a. s., Kladno 3;  Patologicko‑anatomické oddělení, Nemocnice Na Bulovce, Praha 4;  Patologicko‑anatomické oddělení, Oblastní nemocnice Kladno, a. s., Kladno 5
Published in: Ces Urol 2017; 21(4): 299-304
Category: Case report

Overview

We present a case report of a 72-year old male with a long urological history (prostate adenocarcinoma after radical prostatectomy with rising PSA level and urothelial carcinoma pTa low grade with one recurrence) who underwent reconstructive surgery for a left thumb metastasis of a clear cell renal cell carcinoma. Repeated CT scans showed two tiny lesions in both kidneys during follow-up. Nephron-sparing surgery of the right kidney and left-sided nephroureterectomy in two sessions proved a bilateral clear cell renal cell carcinoma pT1a. The patient underwent genetic analysis by the sequence capture panel CZECANCA targeting 219 susceptibility genes to reveal a highly presumable hereditary cancer syndrome, but no significant mutation was found.

Kez words:
Solitary skeletal metastasis, bilateral kidney cancer, clear cell renal cell carcinoma pT1a, uro-oncological triplicity.


Sources

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Labels
Paediatric urologist Nephrology Urology

Article was published in

Czech Urology

Issue 4

2017 Issue 4

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