Paratesticular malignant mesothelioma
Authors:
Gabriela Čečerle 1; Vladimír Šámal 1,2; Jan Mečl 1
Authors‘ workplace:
Urologické oddělení, Krajská nemocnice Liberec, a. s.
1; Urologická klinika Fakultní nemocnice a Lékařské fakulty UK, Hradec Králové
2
Published in:
Ces Urol 2017; 21(4): 305-309
Category:
Case report
Overview
Paratesticular malignant mesothelioma is an extremely rare type of mesothelioma with limited number of published cases. The origin of this cancer is most often associated with exposure to asbestos with long latency between exposure and diagnosis. We present the case of an 80-years -old patient with hydrocele. Aspiration of this extremly large of the hydrocele was performed a few times prior surgery. We found large septated, haemorrhagic hydrocele with significantly thickened extranal layers of the testis, smaller testicle of solid consistency and atrophic epididymis. We indicated orchiectomy due to perioperative finding considering the age of the patient. Histopathological analysis showed malignant mesothelioma of tunica vaginalis. Scrotal resistence was detected in the 6-month follow up. The resistence was histologically confirmed as recurent malignant mesothelioma after extirpation. Patient is under actively surveillance.
Key words:
Mesothelioma, hydrocele, paratesticular tumours, surgery.
Sources
1. Špelda S, Skřičková J, Staňková Y. Maligní pleurální mezoteliom. Onkologická péče 2008; 12(4): 10–13.
2. Ahmed I, Ahmed Tipu S, Isthiaq S. Malignant mesothelioma. Pak J Med Sci. 2013; 29(6): 1433–1438.
3. Mrinakova B, Kajo K, Ondrusova M, Simo J, Ondrus D. Malignant mesothelioma of tunica vaginalis testis.A clinopathologic Analysis of two cases with a rewiew of the literature. Klin Onkol. 2016; 29(5): 369–374.
4. Kao SC, Reid G, van Zandwijk N, Henderson DW, Klebe S. Molecular biomarkers in malignant mesothelioma: state of the art. Pathology 2011; 43(3): 201–212.
5.Winstlanley AM, Ladon G, Berney D, et al. The immonohistochemical profile of malignant mesotheliomas of tunica vaginalis: a study of 20 cases. Am J Surg Pathol 2006; 30(1): 1–6.
6. Jones MA, Young RH, Scully RE. Malignant mesothelioma of tunica vaginalis. A clinicopathologic analysis of 11 cases with review of the literature. Am J Surg Pathol 1995; 19(7): 815–825.
7. Hamm M, Rupp C, Rottger P, Rathert P. Malignant mesothelioma of tunica vaginalis testis. Chirurg 1999; 70(3): 302–305.
8. Chen JL, Hsu YH. Malignant mesothelioma of the tunica vaginalis testis: a case report and literature review. Kaohsiung J Med Sci. 2009; 25(2): 77–81.
9. Priester P, Kopecký J, Prošvicová J, et al. Cutaneous recurrence of malignant mesothelioma of tunica vaginalis testis:a rare case report. Onkologie 2012; 35(1–2): 46–48.
10. Mirabella F. Malignant mesothelioma of the tunica vaginalis of the testis. Here again asbestos? Minerva Med. 1991; 82(11): 765–770.
11. Wein AJ, Kavoussi LR, Norvick AC, et al. Campbell-Walsh Urology Tenth edition, Volume one, Philadelphia, Elsevier Saunders; 2012 Chapter 31, 861.
12. Mrinakova B, Ondrus D, Kajo K, et al. Paratesticular mesothelioma in young age. Case report. Klin Onkol. 2012; 25(4): 290–293.
13. Li X, Brownlee NA, Sporn TA, Mahar A, Roggli VL. Malignant (diffuse) mesothelioma in patients wth hematologic malignancies: A clinicopathologic study of 45 cases. Arch Pathol Lab Med. 2015; 139(9): 1129–1136.
14. Gurdal M, Erol A. Malignant mesothelioma of tunica vaginalis testis associated with long-lasting hydrocele: Could hydrocele be an etiological factor? Int Urol Nephrol 2001; 32: 678–679.
15. Jankovichova T, Jankovich M, Ondrus D, et al. Extremely rare tumour – malignant mesothelioma of tunica vaginalis testis. Bratisl Lek Listy 2015; 166(9): 574–576.
16. Berlotto M, Boulay-Coetta I, Butini R, et al. Imaging of msothelioma of tunica vaginalis testis. Eur Radiol 2016; 26(3): 631–638.
17. Garriga V, Serrano A, Marin A. et al. US of tunica vaginalis testis: anatomic relationshipsand pathologic conditions. Radiographics 2009; 29(7): 2017–2032
18. Gupta NP, Agrawal AK, Sood S, Hemal AK, Nair M. Malignant mesothelioma of tunica vaginalis testis: a report of two cases and review of literature. J Surg Onkol 1999; 70(4): 251–254.
19. Carp NZ, Petersen RO, Kussiak JF, Greenberg RE. Malignant mesothelioma of tunica vaginalis testis. J Urol 1990; 144(6): 1475–1478.
20. Sawada K, Inoue K, Ishihara T, et al. Multicystic malignant mesothelioma of tunica vaginalis with an unsually indolent clinical course. Hinyokika Kiyo 2004; 50(7): 511–513.
21. Andresen ED, Henning G, Uhlman MA, Gupta A. Malignant mesothelioma of tunica vaginalis: a rare case report and descrption of multimodal treatment. Can J Urol 2016; 23(6): 8585–8589.
22. Krolupper M, Benková K, Novák J. Paratestikulární maligní mezoteliom: kazuistika. Ces Urol 2007; 11(3): 98–100.
Labels
Paediatric urologist Nephrology UrologyArticle was published in
Czech Urology
2017 Issue 4
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