PLOS Genetics - Číslo 9/2011

Viewpoints

32767

Temporal Trends in Results Availability from Genome-Wide Association Studies

Research Article

32767

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD

Genetic Variants at Chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 Influence the Risk of Breast Cancer in Men

Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease

Genetic Association for Renal Traits among Participants of African Ancestry Reveals New Loci for Renal Function

Transcriptome Kinetics Is Governed by a Genome-Wide Coupling of mRNA Production and Degradation: A Role for RNA Pol II

Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

Heterozygous Mutations of Are Associated with an Increased Risk of Isolated Metopic Craniosynostosis in Humans and Mice

Study of FoxA Pioneer Factor at Silent Genes Reveals Rfx-Repressed Enhancer at and a Potential Indicator of Esophageal Adenocarcinoma Development

Cholesterol Metabolism Is Required for Intracellular Hedgehog Signal Transduction

Produces a Long Noncoding RNA and Has General Functions in the Germline, Stem Cells, and Brain

Age-Dependent Recombination Rates in Human Pedigrees

Sequence Conservation and Functional Constraint on Intergenic Spacers in Reduced Genomes of the Obligate Symbiont

Sex Chromosome Mosaicism and Hybrid Speciation among Tiger Swallowtail Butterflies

A Negative Feedback Loop That Limits the Ectopic Activation of a Cell Type–Specific Sporulation Sigma Factor of

Phased Whole-Genome Genetic Risk in a Family Quartet Using a Major Allele Reference Sequence

Mutations in or near the Transmembrane Domain Alter PMEL Amyloid Formation from Functional to Pathogenic

Inactivation of Alters Melanosome Shape But Has Only a Subtle Effect on Visible Pigmentation

Novel Interactions between Actin and the Proteasome Revealed by Complex Haploinsufficiency

Germline Genetic Variants Disturbing the /LIN28 Double-Negative Feedback Loop Alter Breast Cancer Susceptibility

Separation of Recombination and SOS Response in RecA Suggests LexA Interaction Sites

Inference of Relationships in Population Data Using Identity-by-Descent and Identity-by-State

Misregulation of Scm3p/HJURP Causes Chromosome Instability in and Human Cells

A Noncoding Point Mutation of Causes Multiple Developmental Malformations and Obesity in Twirler Mice

The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO

A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection

Bacterial Communities of Diverse Species: Ecological Context of a Host–Microbe Model System

A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci

Elongator Complex Influences Telomeric Gene Silencing and DNA Damage Response by Its Role in Wobble Uridine tRNA Modification

Elevated Proteasome Capacity Extends Replicative Lifespan in

Genome-Wide Analysis of Heteroduplex DNA in Mismatch Repair–Deficient Yeast Cells Reveals Novel Properties of Meiotic Recombination Pathways

MicroRNA Predictors of Longevity in

An Iterative Genetic and Dynamical Modelling Approach Identifies Novel Features of the Gene Regulatory Network Underlying Melanocyte Development

Atypical AT Skew in Firmicute Genomes Results from Selection and Not from Mutation

Retrotransposon-Induced Heterochromatin Spreading in the Mouse Revealed by Insertional Polymorphisms

Genomic Analysis of QTLs and Genes Altering Natural Variation in Stochastic Noise

The Abnormal Phenotypes of Cartilage and Bone in Calcium-Sensing Receptor Deficient Mice Are Dependent on the Actions of Calcium, Phosphorus, and PTH

Cell Type–Specific Transcriptome Analysis Reveals a Major Role for and miR-200b in Mouse Inner Ear Morphogenesis

Essential Roles of BCCIP in Mouse Embryonic Development and Structural Stability of Chromosomes

IAP1-Mediated Ubiquitylation Controls Activation of the Initiator Caspase DRONC Independent of Protein Degradation

VANG-1 and PRKL-1 Cooperate to Negatively Regulate Neurite Formation in

The Receptor Tyrosine Kinase Alk Controls Neurofibromin Functions in Drosophila Growth and Learning

Comparative and Functional Genomics of PD630 for Biofuels Development

Identification of Type 1 Diabetes–Associated DNA Methylation Variable Positions That Precede Disease Diagnosis

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells

Genetic Effects at Pleiotropic Loci Are Context-Dependent with Consequences for the Maintenance of Genetic Variation in Populations

Genome-Wide Association Study Identifies Four Loci Associated with Eruption of Permanent Teeth

Bmp and Nodal Independently Regulate Expression to Maintain Unilateral Nodal Activity during Left-Right Axis Specification in Zebrafish

Inter-Allelic Prion Propagation Reveals Conformational Relationships among a Multitude of [] Strains

Emergence and Modular Evolution of a Novel Motility Machinery in Bacteria

Histone Methyltransferase MET-2 Shields the Male X Chromosome from Checkpoint Machinery and Mediates Meiotic Sex Chromosome Inactivation

PLOS Genetics

2011 Číslo 9

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