Genetic Profile and Treatment of NSCLC
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Complete remission of ALK-positive lung cancer in a patient after multiple lines of targeted therapy – a case study
Targeted treatment for driving oncogenic mutations has significantly improved outcomes for patients with ALK-positive non-small cell lung cancer (NSCLC) as well. A case study was recently published in the journal Frontiers in Oncology of a patient with advanced disease who achieved complete remission after several lines of therapy.
Finding Balance Between Intracranial Efficacy and Adverse Effects of ALK Kinase Inhibition
More than 7 years – that is the current median survival of patients with non-small cell lung cancer…
Lorlatinib in a Patient with Meningeal Carcinomatosis – Case Report
The prognosis of patients with meningeal carcinomatosis is unfavorable. The following case report…
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Targeted DNA Sequencing Helps Find Targeted Therapy for Patients with NSCLC
Gene sequencing has become a key tool in deciding the treatment for patients with non-small…
Third Generation Targeted Therapy for ROS1-Positive NSCLC
The potent third-generation tyrosine kinase inhibitor, lorlatinib, has shown activity in…
Lorlatinib as an Alternative to CNS Radiotherapy in Patients with NSCLC − Case Studies
Two remarkable case studies from authors at the Netherlands Cancer Institute Antoni van…
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- Screening using NGS in patients with metastatic NSCLC – initial results from the ALK-positive cohort
- Brain Metastases Are Not an Absolute Contraindication for Antiplatelet Therapy
- Update of the Blue Book: What's New in the Treatment of Metastatic NSCLC with an ALK Gene Mutation?
- Non-Small Cell Lung Cancer with Estrogen Receptors and ALK Positivity
- Progress on Lorlatinib – What's Next?
- Genetic Profiling Transforms the Diagnosis and Treatment of Cancer Diseases
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