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Key for Patients with PBC are Timely Diagnosis and Assessment of Therapy Effectiveness
Primary biliary cholangitis (PBC) cannot be cured. It progresses slowly and over several decades leads to liver cirrhosis with all its potential consequences, including possible transplantation and the risk of premature death. The foundation of PBC pharmacotherapy is ursodeoxycholic acid (UDCA) and in recent years, obeticholic acid (OCA) has also been available, which European and Czech guidelines recommend as the second-line treatment. One of the symposiums at this year's XLVIII May Hepatology Days also focused on PBC and its therapy, including...
Von Willebrand Disease as a Cause of Abnormal Uterine Bleeding
Abnormal uterine bleeding constitutes a large portion of complaints among women of reproductive…
Negative Symptoms of Schizophrenia and Their Assessment
Schizophrenia is a serious psychiatric disorder with a prevalence of up to 1%. It can manifest with…
Dabigatran vs. Warfarin: What and Why Do Patients Prefer?
The key to adherence to long-term anticoagulant therapy is primarily the satisfaction of patients…
New Recommendations for Intravenous Thrombolysis in the Treatment of Acute Ischemic Stroke – ESO Guidelines 2021
Intravenous thrombolysis is the only approved systemic reperfusion therapy for patients with acute…
Alpha-1 Antitrypsin Deficiency and Lung Disease in Patients with Primary Immunodeficiencies
Alpha-1 antitrypsin deficiency (AATD) plays a significant role in the pathogenesis of pulmonary…
Can identifying alpha-1 antitrypsin deficiency before liver transplantation extend survival?
Alpha-1 antitrypsin deficiency (AATD) can manifest (among other things) as liver cirrhosis. The…
Expression of PD-L1 as a Predictive Biomarker for Therapy Selection in mRCC
A newly published systematic review and meta-analysis of studies involving patients with metastatic…
Efficacy and Safety of Axitinib in Higher Lines of Renal Carcinoma Treatment in Real Practice
Greek authors published a retrospective study from a single institution and demonstrated that…
Cardiovascular Risks in Schizophrenics: What Are They Related To and How To Eliminate Them?
Schizophrenia affects about 1% of the population. This disease is associated, among other things,…