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Ureteroscopic Biopsy of Upper Urinary Tract Tumors: Endoscopic and Cytologic Techniques


Authors: D. H. Bagley;  K. A. Healy;  N. Kleinmann;  M. Bibbo
Authors‘ workplace: Department of Urology, Thomas Jefferson University
Published in: Urol List 2012; 10(2): 26-30

Overview

Ureteroscopic biopsy is an essential step in the diagnosis of upper urinary tract tumors. Alternative moda­lities including voided urine and contrast imaging have proven inaccurate for diagnosis. Systematic “no touch” ureteroscopic techniques should be used to survey the involved upper tract. Tumor biopsy may be most efficiently performed with a flat wire basket or cup forceps. Brushes do not provide an adequate sample. All specimens should be delivered fresh in normal saline to the Cytopathology laboratory as soon as possible for tissue preservation. Samples are then prepared using the Cytospin technique, and a cell block is also prepared if any macroscopically visible tissue is present.

Key words:
ureteroscopy, ureter, tumor, biopsy, cytology


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