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THE MODERN ENDOCRINE EVALUATION OF THE INFERTILE MALE


Authors: C. Niederberger
Authors‘ workplace: College of Engineering ;  University of Illinois at Chicago ;  Department of Bioengineering ;  College of Medicine ;  University of Illinois at Chicago ;  Department of Urology
Published in: Urol List 2010; 8(4): 40-42

Overview

The evaluation and treatment of male infertility has undergone a revolution in the past 2 decades. The ability to use extraordinarily small amounts of sperm, sperm derived from the testis, and even dead sperm, to successfully create pregnancies with in-vitro fertilization and intracytoplasmic sperm injection fundamentally altered how infertile men should be evaluated. Even small changes in the hormonal milieu may result in profound prognostic and therapeutic implications. Based on the biological foundations of the male endocrine system, a rational approach to the evaluation of the infertile male is presented. This approach involves a thorough investigation into biologically active androgen, assessment of spermatogenic function, and appraisal of the involvement of related systems such as aromatase, thyroid and adrenal activity. With an accurate diagnosis, the clinician may then proceed with a sensible therapeutic approach to the infertile male.

KEY WORDS:
male infertility - endocrine evaluation - testosterone - testis


Sources

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Paediatric urologist Urology
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