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První zkušenosti jednoho centra s použitím přípravku Octaplas® v léčbě pacientky s vrozenou formou trombotické trombocytopenické purpury


Authors: Z. Čermáková 1;  Š. Blahutová 2;  M. Kořístka 2;  R. Hrdličková 2
Authors‘ workplace: Lékařská fakulta Ostravské univerzity 1;  Krevní centrum Fakultní nemocnice Ostrava 2
Published in: Transfuze Hematol. dnes,18, 2012, No. 4, p. 162-164.
Category: Comprehensive Reports, Original Papers, Case Reports

Overview

Congenital form of TTP (Upshaw-Schulman syndrome) is a severe, life-threatening disease in which plasma remains the first-choice treatment. Patients are dependent on regular therapeutic plasma exchange or plasma infusion. A plasma volume of 1-1.5 is usually substituted by donors’ quarantine plasma. In these patients, secondary mild/severe side effects (allergic reactions, transfusion-induced acute lung injury) are very often observed. The authors comment on their first experience with the use of Octaplas® (Octapharma, Vienna, Austria).

Key words:
thrombotic thrombocytopenic purpura, Octaplas, therapeutical plasma exchange


Sources

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