Relation of quality of life and a type of treatment in women with breast carcinoma: A pilot study

Czech version

Authors: Kateřina Skřivanová ¹; Ľubomíra Anderková ²; Dagmar Brančiková ³; Marcela Bendová ⁴; Nela Elfmarková ²; Tomáš Svěrák ²; Hana Peterková ¹; Jiří Jarkovský ⁵; Klára Benešová ⁵; Luboš Minář ⁴; Ladislav Dušek ⁵
Authors‘ workplace: Ústav psychologie a psychosomatiky LF MU, Brno, vedoucí pracoviště doc. MUDr. Tomáš Kašpárek, Ph. D. ¹; Central European Institute of Technology (CEITEC) MU, Brno ²; Interní hematologická a onkologická klinika LF MU a FN, Brno, přednosta prof. MUDr. Jiří Mayer, CSc. ³; Gynekologicko-porodnická klinika LF MU a FN, Brno, přednosta prof. MUDr. Pavel Ventruba, DrSc., MBA ⁴; Institut biostatistiky a analýz LF MU, Brno, ředitel doc. RNDr. Ladislav Dušek, Ph. D. ⁵
Published in: Prakt Gyn 2015; 19(1): 25-37
Category: Oncogynecology: Original Article

Overview

The aim of the pilot study was to assess quality of life (QoL) in patients with breast carcinoma in relation to treatment modalities and their combinations. A total of 71 patients with breast carcinoma participated in this study. QoL was assessed using the 36-item Short-Form Health Survey (SF-36), Life Satisfaction Questionnaire and Czech research version of Functional Assessment of Breast Cancer Therapy (FACT-B). The average time from diagnosis at the time of QoL assessment was 4.5 years. Mann-Whitney U test was used to test the differences in QoL between groups of patients with different type of therapy and Kruskal-Wallis test for combinations of therapies. A relation between quality of life and a treatment modality was found for questionnaire SF 36 – for the dimension of emotional functional role and operation treatment (higher quality of life in operated patients, p = 0.049), for questionnaire FACT-B – physical condition and chemotherapy (higher quality of life in patients without chemotherapy, p = 0.012), for FACT-B – social/family condition and operation treatment (higher quality of life in operated patients, p = 0.036), for FACT-G score and operation treatment (higher quality of life in operated patents, p = 0.049) and further for Life Satisfaction Questionnaire – for the dimension of health and treatment combination (the highest quality of life in case of the combination of operation, chemotherapy, radiotherapy, biological and hormonal therapy, the lowest quality of life in case of the combination of the previous without biological therapy, p = 0.027). Additionally, we described type and occurrence of side effects of treatment modalities. Generally we found higher QoL in operated patients and lower in patients who underwent chemotherapy, however our findings require further research verifications.

Key words:
breast carcinoma – quality of life – oncological treatment – treatment side effects

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