Supportive Hormonal Therapy in Assisted Reproduction Programme
Authors:
R. Hudeček; P. Ventruba; I. Crha
Authors‘ workplace:
Gynekologicko-porodnická klinika LF MU a FN Brno
Published in:
Prakt Gyn 2005; 9(5): 6-9
Overview
The authors present review of therapeutic possibilities of supportive hormonal therapy in an assisted reproduction (AR) programme based on their own clinical groups of patients and current literature data. They deal with possibilities of use of hormonotherapy to solve the individual dysfertility factors with respect to their potential influence on the result of in vitro fertilisation (IVF) cycle. Complete review of stimulation protocols used to induce folliculogenesis and ovulation is supplemented with possible supportive pharmacotherapeutic procedures that find use prior to respective treatment IVF cycle, in its course and in the area of immunomodulation of incipient pregnancy after IVF. The questions of the treatment of ovarian, tubal and uterine factors of infertility, the influence of patient age on the AR result, the treatment of endometriosis and andrologic factor are discussed.
Keywords:
assisted reproduction – hormonal therapy – in vitro fertilisation
Sources
1. Belaisch AJ, Devaux A, Ayel JP, Nouzov J. Women of 40 and older in i.v.f. and i.c.s.i.: the FIVNAT data. Gynecol Obstet Fertil 2004; 32(9): 730-736.
2. Cibula D, Fanta M, Hill M, Sindelka G, Skrha J, Zivny J. Insulin sensitivity in non-obese women with polycystic ovary syndrome dutiny treatment with oral contracveptives containing low – androgeni progestin. Hum Reprod 2002; 17(1): 76-82.
3. Cicinelli E, Cignarelli M, Resta L et al. Effects of the repetitive administration of progesterone by nasal spray in postmenopausal women. Fertil Steril 1993; 60(6): 1020-1024.
4. Crha I, Ventruba P, Hudeček R, Žáková J, Petrenko M. Současná spermobanka – screening dárců a provoz. Asist Rep 1999; 9: 18-20.
5. Damario MA, Barmat L, Liu HC et al. Dual suppresion with oral contraception and gonadotrophin releasing – hormone agonists improves in-vitro fertilisation outcome in high responders patiens. Hum Reprod 1997; 12: 2359-2365.
6. ESHRE Capri work group. Ovarial and endometrial function during hormonal contraception. Hum Reprod 2001; 16(7): 1527-1535.
7. Franks AL et al. Contraception and ectopic pregnancy risk. Amer J Obstet Gynec 1990; 163: 1123.
8. Gerhard I, Mastthes J, Runnebaum B. The induction of ovulation with pulsatile gonadotrophin releasing hormone administration in hyperandrogenic women after down-regulation with buserelin or suppresion with an oral contraceptive. Hum Reprod 1993; 8: 2033-2038.
9. Hudeček R, Ventruba P, Šarmanová J, Šarman Z, Solár T. Analýza faktorů ovlivňujících výsledky asistované reprodukce pomocí systému pro dolování znalostí z dat SHLUK a neuronové sítě NEUL 3. Závěrečná zpráva grantu IGA MZ ČR 4916-3.
10. Hudeček R, Ventruba P, Juránková E et al. Terapeutické možnosti asistované reprodukce u perimenopauzálních žen. Prakt Gynek 2004; 8(6): 6-9.
11. Lockhatt FB, Emembolu J, Konje JC. The evaluation of the effectiveness of an intrauterine administrated levonorgestrel in the symptomatic treatment of endometriosis and in the staging of the disease. Human Reprod 2004; 19(1): 179-184.
12. Lourdes IE, Francis Z. Flutamide-Metformin plus an oral contraceptive (OC) for young women with polycistic ovary syndrome: switch third- to fourth- generation OC reduces body adiposity. Hum Reprod 2004; 19(8): 1725-1727.
13. Navot D, Bergh P, Williams M et al. Poor oocyte quality rather than implantation failure as a cause of age-related decline in female infertility. Lancet 1991; 337(8754): 1375-1377.
14. Padilla SL, Bayati J, Garcia JE. Prognostic value of the early serum estradiol response to leuprolide acetate in in vitro fertilization. Fertil Steril 1990; 53(2): 288-94.
15. Panayiotis MZ, Michel AA, Khalied K. Erectile dysfunction: Seminal characteristic of men undergoing infertility treatment using viagra. Fertil Steril 2002; 80(3): 207.
16. Reyes P, Sanchez-Vazquez ML, Merchant-Larios H et al. Effect of heparin-reduced glutathione on hamster sperm DNA unpacking and nuclear swelling. Arch Androl 1996; 37(1): 33-45.
17. Rolf C, Behre HM, Nieschlag E. Reproductive parameters of older compared to younger men of infertile couples. J Androl 1996; 19(3): 135-142.
18. Rubin GL et al. Oral contraceptives and pelvic inflamatory disease. Amer J Obstet Gynec 1982; 144: 630.
19. Sauer MV, Paulson RJ, Lobo RA. Pregnancy after age 50: application of oocyte donation to women after natural menopause. Lancet 1993; 341: 321-323.
20. Schwarz D, Mayaux MJ. Female fecundity as a function of age: results of artificial insemination in 2193 nulliparous women with azoospermic husbands. Federation CECOS. N Engl J Med 1982; 306(7): 404-406.
21. Ventruba P, Crha I, Muller P, Mlyncek M. Treatment of pelvic endometriosis with goserelin, an LHRH agonist. Čes gynek 1996; 61(1): 11-16.
22. Ventruba P, Višňová H, Hudeček R. Kam směřuje vývoj asistované reprodukce v České republice? Národní registr ART 1993–1996. Prakt Gyn 1997; 1(5): 20.
23. Ventruba P, Mardesic T, Pilka L et al. Registr asistované reprodukce: výsledky a analýza komplikací. Čes Gynek 1998; 63(2): 107-110.
24. Ventruba P, Višňová H, Hudeček R, Lokajová J. 10 let národního registu asistované reprodukce v ČR. Asist Reprod 1997; 7 (1): 6-7.
25. Ventruba P, Višňová H, Crha I. Embryoprotektivní imunomodulace. Asist Reprod 2002; 12(1): 8.
26. Zahrádková M, Višňová H, Petrenko M, Ventruba P. Hysteroskopické nálezy v dutině děložní u neplodných žen. In: Sb. abstrakt Celostátní konference ČGPS – Gynekologická endoskopie 1999: 14.
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Practical Gynecology
2005 Issue 5
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