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Genetic Predisposition for Multiple Metabolic Syndrome - Part 3: Lipid, Lipoprotein andApolipoprotein Metabolism


Authors: J. †šobra;  R. Češka
Authors‘ workplace: III. interní klinika 1. LF UK a VFN, Praha
Published in: Čas. Lék. čes. 1999; : 136-141
Category:

Overview

The author discusses metabolic processes during exogenous and endogenous lipid transport and deviations in themetabolism of lipids, lipoproteins and apolipoproteins in multiple metabolic syndrome and in so-called diabeticdyslipidaemia. Specific phenotypic manifestations of diabetic dyslipidaemia include hypertriacylglycerolaemia,hypercholesterolaemia, elevated plasma levels of LDL-cholesterol and apolipoprotein B and reduced levels ofHDL-cholesterol and apolipoprotein B and reduced levels of HDL-cholesterol and apolipoprotein A-I. Other recentfindings relating to this syndrome include evidence of elevated concentrations of small and dense LDL micelles (

Key words:
multiple metabolic syndrome, metabolism of lipids, lipoproteins and apolipoproteins, small denseLDL particles, modified LDL, diabetic dyslipidaemia.

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Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist
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