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Etiopathogenesis and Treatment of Dermatophytoses of the Nails


Authors: J. Buchvald
Authors‘ workplace: Dermatovenerologická klinika LF UK a FN, Bratislava
Published in: Čas. Lék. čes. 1999; : 152-155
Category:

Overview

The importance of mycotic infections of the skin and its adnexa has a rising trend. The causal agents are not onlydermatophytes and candidae but to an increasing extent opportune fungal microorganisms. Most frequently thesediseases develop during intense immunosuppressive treatment, e.g. in oncological, oncohaematological diseases andin developed AIDS syndrome. In addition to the reduced defence capacities of the organism favourable conditionsare created e.g. by antibiotic treatment, treatment with female hormones, unsuitable clothing, obesity, a certain partis played also by occupational predisposition.Treatment of onychomycoses is complicated and difficult. Before griseofulvin was available there was only surgicalablation and treatment with keratolytics. At present a number of substances with marked fungistatic effects isavailable. The author mentions: griseofulvin, ketoconazole, fluconazole, itraconazole (azole derivatives), allylamines(terbinafine-Lamisil). He discusses the mode of administration, dosage and undesirable effects. The recent antimy-cotics are ciclopiroxolamines (Batrafen) and amorolfin (Loceryl) in the form of lac.

Key words:
dermatophytoses, immunosuppressive agents, cytostatics, X-ray irradiation, fungicides, undesirableeffects.

Full text is not available online.
If interested in a scan of this journal, contact NTO ČLS JEP.

Labels
Addictology Allergology and clinical immunology Angiology Audiology Clinical biochemistry Dermatology & STDs Paediatric gastroenterology Paediatric surgery Paediatric cardiology Paediatric neurology Paediatric ENT Paediatric psychiatry Paediatric rheumatology Diabetology Pharmacy Vascular surgery Pain management Dental Hygienist
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