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Overlap syndrome SLE – ANCA associated vasculitis


Authors: Martina Skácelová 1;  Pavel Horák 1;  Jana Janková 2
Authors‘ workplace: III. interní klinika – nefrologická, revmatologická a endokrinologická, FN a LF UP Olomouc 1;  Ústav klinické a molekulární patologie, LF UP Olomouc 2
Published in: Vnitř Lék 2021; 67(1): 58-61
Category: Case Reports

Overview

Incidence of ANCA antibodies in patients with systemic lupus erythematosus (SLE) is described in 24–31 %, but they are not related to the distribution and severity of organ involvement in SLE; the routine monitoring is not recommended. Overlap syndrome of systemic lupus erythematosus and ANCA associated vasculitis (AAV) is rare. The difficult diagnosis and treatment of this syndrome is described in this case report of the patient with SLE and severe kidney involvement resulting from AAV.

Keywords:

ANCA associated vasculitis – overlap syndrome – systemic lupus erythematosus.


Sources

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