Antiplatelet thromboprophylaxis of arterial vascular diseases and organovascular ischemic diseases
Authors:
Peter Gavorník 1; Andrej Dukát 1,2; Ľudovít Gašpar 1,3; Eva Gavorníková 1,4; Naďa Hučková 1,5; Anna Petrášová 6; Gabriela Gubo 1; Iveta Gašparová 1,7; Lujza Sabolová 8
Authors‘ workplace:
Angiologická sekcia Slovenskej lekárskej komory, Bratislava, Slovenská republika
1; V. interná klinika LF UK a UNB, Bratislava, Slovenská republika
2; I. interná klinika LF UK a UNB, Bratislava, Slovenská republika
3; Ambulancia všeobecného lekárstva pre dospelých, Poliklinika Ružinov, Bratislava, Slovenská republika
4; III. interná klinika LFUK a UNB, Bratislava, Slovenská republika
5; Lekáreň Salvator, Prosalute, Modra, Slovenská republika
6; Ústav lekárskej biológie, genetiky a klinickej genetiky LF UK, Bratislava, Slovenská republika
7; Onkologický ústav svätej Alžbety, Bratislava, Slovenská republika
8
Published in:
Vnitř Lék 2017; 63(2): 124-132
Category:
Guidelines
Overview
Antiplatelet therapy by acetylsalicylic acid (ASA, aspirin) provided pivotal advances in the prevention and treatment of organovascular (angiovascular, cardiovascular, cerebrovascular, extremitovascular, renovascular, genitovascular, mesenteriointestinokolonovascular, bronchopulmovascular, oculovascular, otovascular and other) arterial ischemic diseases. Currently available antiplatelet drugs have some limitations which might be overcomed by improved dosing regimens, use of combination of agents affecting different platelet functions and, in particular, by the new antiplatelet drugs (new arterial antithrombotics) with distinct pharmacodynamic properties offering new advantages, including faster onset of action, greater potency, and reversibility of effects.
Key words:
arteriothromboprophylaxis – arterial thrombosis – classic antiplatelet drugs – new antiplatelet agents – organovascular arterial diseases
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