Vitamin D in aortic stenosis

Czech version

Authors: K. Linhartová ¹; G. Štěrbáková ²; R. Čerbák ³
Authors‘ workplace: Kardiologická klinika 2. lékařské fakulty UK a FN Motol Praha, přednosta prof. MUDr. Josef Veselka, CSc. ¹; I. interní klinika Lékařské fakulty UK a FN Plzeň, přednosta prof. MUDr. Martin Matějovič, Ph. D. ²; Centrum kardiovaskulární a transplantační chirurgie Brno, ředitel doc. MUDr. Petr Němec, CSc. ³
Published in: Vnitř Lék 2012; 58(5): 390-392
Category: Appendix: Vitamin D

Overview

Aortic stenosis is the third most common cardiovascular disease and the most commonly operataed valve disease in developed countries. Progressive valve calcification leading to significant flow obstruction is the main pathogenetic feature. Dysregulation of the systemic calcium-phosphate metabolism with low vitamin D level is a possible risk factor of aortic stenosis even in patients with preserved renal function. This hypothesis deserves further clinical and experimental study.

Key words:
calcification of the aortic valve – vitamin D – aortic stenosis

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