Calcitriol endocrine microsystems – developmental aspects and prerequisites for their lifelong functionality

Czech version

Authors: B. Kalvachová
Authors‘ workplace: Endokrinologický ústav Praha, ředitelka doc. RNDr. Běla Bendlová, CSc.
Published in: Vnitř Lék 2012; 58(5): 396-399
Category: Appendix: Vitamin D

Overview

New findings regarding the local synthesis of calcitriol, its binding on nuclear receptors and its regional tissue effects have led to discovery of its endocrine microsystems. Their application in growing organisms and their lifelong functionality provide possible preventive and treatment modalities in multiple ailments, mostly by natural and minimally expensive means.

Key words:
calcitriol endocrine microsystems – children – saturation factors – cholecalciferol daily need – supplementation

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