Chronic autoimmune thyroiditis and connective tissue system diseases

Czech version

Authors: Ž. Macejová; K. Benhatchi; I. Lazúrová
Authors‘ workplace: I. interná klinika Lekárskej fakulty UPJŠ a FN L. Pasteura, Košice, Slovenská republika, prednosta prof. MUDr. Ivica Lazúrová, CSc.
Published in: Vnitř Lék 2006; 52(9): 801-804
Category: Review

Overview

Autoimmune thyroiditis is often related to non-specific autoimmune organ diseases such as Rheumatoid Arthritis, Sjögren’s syndrome, systemic sclerosis, Systemic Lupus Erythematosus or polymyalgia rheumatica. Etiology of autoimmune diseases has not been clearly discovered yet. In many aspects, mechanisms leading to organ-specific autoimmune diseases are identic with mechanisms causing organ-nonspecific autoimmune disease. In many cases genetic disposal combined with specific antigens can be seen. Another possible factor in terms of endogenesis is genus. External factors are important too, such as undergoing infection, stress situations, exposion to ultraviolet radiation. Authors of this work summarize facts about chronic autoimmune thyroiditis and system connective tissue disease. The most literature supports more frequent appearance of these diseases, while the thyroiditis can appear both in clinical form with typical symptoms and in subclinical form.

Key words:
chronic autoimmune thyroiditis – system connective tissue disease – subclinical hypothyreoism

Sources

1. Tajtáková M, Langer P, Fodor G et al. Epidemiological profile of thyroid volume and disorders in Slovakia. Vnitř Lék 2000; 46: 743-744.

2. Rovenský J, Payer J, Rybár I et al. Reumatologické prejavy u pacientov s endokrinnými chorobami. In: Rovenský J, Pavelka K. Klinická Reumatológia. Martin: Osveta 2000: 615-628.

3. Gashes F, Delaire L, Nadalon S et al. Fréquence des maladie auto-immunes chez 218 patients atteints de pathologie thyroidiennes auto-immunes. Rev Med Interne 1988; 19: 173-179.

4. Gordon T, Isemberg D. The endocrinologic associations of the autoimmune rheumatic diseases. Semin Arthritis Rheum 1987; 17: 58-70.

5. Coll J, Anglada J, Tomas S et al. High prevalance of subclinical Sjögrens syndrome features in patients with autoimmune thyroid disease. J Rheumatol 1997; 24: 1719-1724.

6. Punzi L, Michelotto M, Pianon M et al. Clinical, laboratory and immunogenetic aspects of arthritis associated with chronic lymfocytic thyroiditis. Clin Exp Rheumatol 1997; 15: 373-380.

7. Tunc R, Gonen MS, Acbay O et al. Autoimmune thyreoiditis and anti-thyreoid antibodies in primary Sjögren syndrome: a case-control study. Ann Rheum Dis 2004; 63: 575-577.

8. Silman AJ, Ollier WER, Bubel MA. Autoimmune thyroid disease and thyroid autoantibodies in rheumatoid arthritis patients and their families. Br J Rheumatol 1989; 28: 18-21.

9. Prahalad S, Shear ES, Thompson SD et al. Increased prevalence of familial autoimmunity in simplex and multiplex families with juvenile rhematoid arthritis. Arthritis Rheum 2002; 46: 1851-1856.

10. Innocencio RM, Romaldini JH, Ward LS. Thyreoid autoantibodies in autoimmune disease. Medicina (B Aires) 2004; 64: 227-230.

11. Deighton CM, Fay A, Walker J. Rheumatoid arthritis in thyroid disease positive and negative same-sexed sibships. Br J Rheumatol 1992; 31: 13-17.

12. Lange U, Boss B, Teichmann J et al. Thyroid disorders in female patients with ankylosing spondylitis. Eur J Med Res 1999; 22: 468-474.

13. Bianchi G, Marchesini G, Zoli M et al. Thyroid involvement in chronic inflammatory rheumatological disorders. Clin Rheumatol 1993; 12: 479-484.

14. Pyne D, Isenberg DA. Autoimmune thyroid disease in systemic lupus erythematosus. Ann Rheum Dis 2002; 61: 70-72.

15. Chan AT, Al-Saffar Z, Bucknall RC. Thyroid disease in systemic lupus erythematosus and rheumatoid arthritis. Rheumatology (Oxford) 2001; 40: 353-354.

16. Weetman AP, Walport M. The association of autoimmune thyroiditis with systemic lupus erythematosus. Br J Rheumatol 1987; 26: 359-361.

17. Macejová Ž, Nagyová I, Trejbal D et al. Vzťah medzi hodnotami prolaktínu a mierou funkčnej neschopnosti hodnotenej dotazníkom HAQ a pacientov s reumatoidnou artritídou. Vnitř Lék 2005; 51: 1260-1265.

18. Kramer CK, Tourinho TF, De Castro WP et al. Association between Systemic lupus erythematosus, Rheuamtoid Arthritis, hyperprolactinemia and thyroid autoantibodies. Archives of Medical Research 2005; 36: 54-58.

19. Morita S, Arima T, Matsuida M. Prevalence of nonthyroid specific autoantibodies in autoimmune thyroid disease. J Clin Endocrinol Metab 1995; 80: 1203-1206.

20. Paggi A, Caccavo D, Ferri GM et al. Anti-cardiolipin antibodies in autoimmune thyroid diseases. Clin Endocrinol 1994; 40: 329-333.

21. Becker KL, Ferguson RH, McConahey WM. The connective tissue diseases and symptomes associated with Hashimoto´s thyroiditis. N Engl J Med 1963; 268: 277-280.

22. Gashes F, Delaire L, Nadalon S et al. Fréquence des maladies autoimmune chez 218 patients de pathologies thyroidienne autoimmunes. Ann Méd Int 1998; 19: 173-179.

23. Kahl LE, Medesger Jr TA, Klein I. Prospective evaluation of thyroid function in patients with systemic sclerosis (scleroderma). J Rheumatol 1998; 13: 103-107.

24. Gordon MB, Klein I, Dekker A et al. Thyroid disease in progressive systemic sclerosis: increased frequency of glandular fibrosis and hypothyroidism. Ann Intern Med 1981; 95: 431-435.

25. Molteni M, Barili M, Eisera N et al. Anti-thyroid antibodies in Italian scleroderma patients: association of anti-thyroid peroxidase (anti-TPO) antibodies with HLA-DR 15. Clin Exp Rheumatol 1997; 15: 529-534.

26. Dent RG, Edwards OM. Autoimmune thyroid disease and polymyalgia rheumatica-giant cell arteritis syndrome. Clin Endocrinol (Oxford) 1978; 9: 215-219.

27. Lahita RG. Sex hormones and the immune system - part 1, human data. Bailiers Clinical Rheumatology 1990; 4: 1-12.

28. Yadim G, Sarov B, Naggan L et al. Natural antibodies in the serum of healthy women, a five year follow-up. Clin Exp Immunol 1989; 75: 325-330.