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Pattern-based approach to duodenitis and duodenopathy


Authors: Ondřej Daum 1,2;  Magdaléna Daumová 1,2;  Marián Švajdler 1,2
Authors‘ workplace: Šiklův ústav patologie LF UK a FN Plzeň 1;  Bioptická laboratoř s. r. o., Plzeň 2
Published in: Čes.-slov. Patol., 58, 2022, No. 2, p. 88-99
Category: Reviews Article

Overview

Duodenum is currently the most popular site to obtain samples of intestinal mucosa for recognition of a disorder leading to malabsorption. Although there are significant overlaps between histological findings described in various non-neoplastic diseases of the duodenum, recognition of one of the six basic morphologic patterns, namely coeliac disease-like pattern, active chronic duodenitis, acute GvHD-like pattern, enteritis with predominant eosinophilic infiltration, enteritis with predominant infiltration by macrophages, and non-inflammatory enteropathy, usually allows diagnostic separation, especially if subtle histological details, clinical setting and serological investigation are taken into account.

Keywords:

endoscopy – Biopsy – duodenum – pattern – duodenitis – duodenopathy


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