#PAGE_PARAMS# #ADS_HEAD_SCRIPTS# #MICRODATA#

The role of endoscopy in non-oncologic gastrointestinal disorders in pediatric patients


Authors: Lucie Gonsorčíková 1;  Silvie Netvalová 1;  Radim Vyhnánek 1;  David Bauer 1;  Ondřej Fabián 2,3
Authors‘ workplace: Pediatrická klinika 1. lékařské fakulty UK a Fakultní Thomayerovy nemocnice, Praha 1;  Pracoviště klinické a transplantační patologie, Institut klinické a experimentální medicíny, Praha 2;  Ústav patologie a molekulární medicíny 3. LF UK a FTN, Fakultní Thomayerova nemocnice, Praha 3
Published in: Čes.-slov. Patol., 58, 2022, No. 2, p. 100-106
Category: Reviews Article

Overview

Gastrointestinal (GIT) diseases represent an important part of pediatric health disorders. The recent years have brought not only significant improvement of digestive endoscopy technologies and a new equipment suitable for pediatric age but also progress in management of diagnostic approach and treatment of the pediatric GIT diseases. In contrast to adult patients, endoscopic examination in pediatrics is in most cases performed for diagnostic, not therapeutical purposes. The histological assessment of biopsy specimens taken during endoscopy therefore forms an integral part of the endoscopic examination and in most cases the diagnosis cannot be concluded without their evaluation. In particular, the clinical gastroenterologist expects from the pathologist a description that will help confirm or contradict the diagnosis considered after the macroscopic examination. In this review, we would like to highlight the most common endoscopic findings of the gastrointestinal tract in pediatric population and the role of histology in determining the correct diagnosis.

Keywords:

endoscopy – Celiac disease – IBD – GIT diseases – gastrointestinal reflux disease – eosinophilic inflammation


Sources

1. Rosen R, Vandenplas Y, Singendonk M et al. Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr 2018; 66(3): 516-554.

2. Arasu TS, Wyllie R, Fitzgerald JF et al. Gastroesophageal reflux in infants and children comparative accuracy of diagnostic methods. J Pediatr 1980; 96(5): 798-803.

3. Lundell LR, Dent J, Bennett JR et al. Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification. Gut 1999; 45(2): 172-180.

4. Ismuil-Beigi F, Horton PF. Pope CE II. Histological consequences of gastroesophageal reflux in man. Gastroenterology 1970; 58: 163- 174.

5. Hradský O, Bajerová K, Bronský J et al. Diagnostika a léčba refluxního onemocnění u dětí: český sjednocený doporučený postup z pohledu gastroenterologa, pneumologa, ORL lékaře, neonatologa a chirurga. Čes-slov Pediat 2016; 71 (1): 5-6.

6. Jeurnink SM, van Herwaarden-Lindeboom MY, Siersema PD, Fischer K, Houwen RH, van der Zee DC. Barrett‘s esophagus in children: does it need more attention? Dig Liver Dis 2011; 43(9) :682-687.

7. Kinoshita Y, Oouchi S, Fujisawa T. Eosinophilic gastrointestinal diseases - Pathogenesis, diagnosis, and treatment. Allergol Int 2019; 68(4): 420-429.

8. Molodecky NA, Soon IS, Rabi DM, Ghali WA et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 2012; 142(1): 46-54.e42

9. Dellon ES, Liacouras CA, Molina-Infante J, Furuta GT et al. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology 2018; 155(4): 1022- 1033.

10. Bolton SM, Kagalwalla AF, Wechsler JB. Eosinophilic Esophagitis in Children: Endoscopic Findings at Diagnosis and Post-intervention. Curr Gastroenterol Rep 2018; 20(1): 4.

11. Liacouras CA, Furuta GT, Hirano I et al. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol 2011; 128(1): 3-20.e6; quiz 21-2.

12. Dellon ES, Kim HP, Sperry SL, Rybnicek DA, Woosley JT, Shaheen NJ. A phenotypic analysis shows that eosinophilic esophagitis is a progressive fibrostenotic disease. Gastrointest Endosc 2014; 79(4): 577-85.e4.

13. Collins MH, Capocelli K, Yang GY. Eosinophilic Gastrointestinal Disorders Pathology. Front Med (Lausanne) 2018; 4: 261.

14. Husby S, Koletzko S, Korponay-Szabó I, Kurppa et al. European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020. J Pediatr Gastroenterol Nutr 2020; 70(1): 141-156.

15. Sierra D, Wood M, Kolli S, Felipez LM. Pediatric Gastritis, Gastropathy, and Peptic Ulcer Disease. Pediatr Rev 2018; 39(11): 542-549.

16. Koletzko S, Richy F, Bontems P, Crone J et al. Prospective multicentre study on antibiotic resistance of Helicobacter pylori strains obtained from children living in Europe. Gut 2006; 55(12): 1711-1716.

17. Jones NL, Koletzko S, Goodman K et al. ESPGHAN, NASPGHAN. Joint ESPGHAN/NASPGHAN Guidelines for the Management of Helicobacter pylori in Children and Adolescents (Update 2016). J Pediatr Gastroenterol Nutr 2017; 64(6): 991-1003.

18. Jabandziev P, Pinkasova T, Kunovsky L et al. Regional Incidence of Inflammatory Bowel Disease in a Czech Pediatric Population: 16 Years of Experience(2002-2017). J Pediatr Gastroenterol Nutr 2020; 70(5): 586-592.

19. Levine A, Koletzko S, Turner D, Escher JC et al. European Society of Pediatric Gastroenterology, Hepatology, and Nutrition. ESPGHAN revised porto criteria for the diagnosis of inflammatory bowel disease in children and adolescents. J Pediatr Gastroenterol Nutr 2014; 58(6): 795-806.

20. Lukáš M. Postavení koloskopie u idiopatických střevních zánětů. Endoskopie 2010; 19(3 a 4): 105-111.

21. Adolph VR, Bernabe K. Polyps in children. Clin Colon Rectal Surg 2008; 21(4): 280-285.

22. Giardiello FM, Hamilton SR, Kern SE, et al. Colorectal neoplasia in juvenile polyposis or juvenile polyps. Arch Dis Child 1991; 66(8): 971- 975.

23. Brosens LA, Langeveld D, van Hattem WA, Giardiello FM, Offerhaus GJ. Juvenile polyposis syndrome. World J Gastroenterol 2011; 17(44): 4839-4844.

24. Cohen S, Hyer W, Mas E, et al. Management of Juvenile Polyposis Syndrome in Children and Adolescents: A Position Paper From the ESPGHAN Polyposis Working Group. J Pediatr Gastroenterol Nutr 2019; 68(3): 453-462.

25. Choi HS, Park YJ, Park JG. Peutz-Jeghers syndrome: a new understanding. J Korean Med Sci 1999; 14(1): 2-7.

Labels
Anatomical pathology Forensic medical examiner Toxicology
Topics Journals
Login
Forgotten password

Enter the email address that you registered with. We will send you instructions on how to set a new password.

Login

Don‘t have an account?  Create new account

#ADS_BOTTOM_SCRIPTS#