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Adenoleiomyomatous Hamartoma of the Lung


Authors: J. Mačák
Authors‘ workplace: Ústav patologie Lékařské fakulty Univerzity Palackého, Olomouc Laboratoř imunohistologických a speciálních metod
Published in: Čes.-slov. Patol., , 2003, No. 4, p. 189-192
Category:

Overview

The author described an adenoleiomyomatous hamartoma of the lung. The hamartoma was wellcircumscribed and measured 2.5x3.0x3.0 cm. This type of hamartoma is a rare lesion in literaturedescribed only in single cases, and without performed immunohistochemistry. In our case, thehamartoma was formed by slit or irregular glandular-like spaces lined by cuboid or columnarepithelial cells. Located around these spaces, fascicles and bundles of smooth muscle tissue witha positive antibody reaction to desmin, smooth muscle actin, and calponin, were found. Reactionwith CD34 and S100 protein antibodies was negative. In the discussion, the author draws attentionto disunity of terms and nomenclature of similar lesions. After three years of post-operativeclinical follow-up, the patient is asymptomatic and without any signs of lung disoder.

Key words:
adenoleiomyomatous hamartoma – lung – morphology – immunohistochemistry

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Anatomical pathology Forensic medical examiner Toxicology
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