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Current views on the pathophysiology, diagnosis and treatment of immune thrombocytopenia in children


Authors: D. Pospíšilová 1;  P. Smíšek 2
Authors‘ workplace: Dětská klinika Fakultní nemocnice a Lékařské fakulty Univerzity Palackého, Olomouc 1;  Klinika dětské hematologie a onkologie 2. LF UK a FN Motol, Praha 2
Published in: Čes-slov Pediat 2021; 76 (8): 460-473.
Category: Review

Overview

The review summarizes the most recent knowledge of the epidemiology, pathophysiology, current diagnostic aproach and treatment strategies in immune thrombocytopenia in children.

Keywords:

splenectomy – Quality of life – Molecular mimicry – immune thrombocytopenia – antiplatelet antibodies – T-cell mediated platelet destruction – platelet desialylation – immunosupressive treatment – TPO mimetics


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